ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: excision repair cross-complementation group 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000311895 ERCC4-001 ENSG00000175595 9606 + 16:13920157-13952345 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000311895
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000311895 0.027±0.00 1.577±0.46 2.929±0.00 1.564±1.18

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000014 IBA single-stranded DNA endodeoxyribonuclease activity
GO:0000109 IDA nucleotide-excision repair complex
GO:0000110 IDA nucleotide-excision repair factor 1 complex
GO:0000712 IBA resolution of meiotic recombination intermediates
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0000723 IMP telomere maintenance
GO:0000724 IMP double-strand break repair via homologous recombination
GO:0000737 IBA DNA catabolic process, endonucleolytic
GO:0000781 IDA chromosome, telomeric region
GO:0000784 IDA nuclear chromosome, telomeric region
GO:0001094 IEA TFIID-class transcription factor binding
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003684 IMP damaged DNA binding
GO:0003697 IDA single-stranded DNA binding
GO:0004518 IEA nuclease activity
GO:0004519 IEA endonuclease activity
GO:0004520 IDA endodeoxyribonuclease activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005669 IEA transcription factor TFIID complex
GO:0006281 IMP:IEA DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 IDA nucleotide-excision repair
GO:0006295 IMP nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 IMP nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0008022 IPI protein C-terminus binding
GO:0009411 IMP response to UV
GO:0009650 IEA UV protection
GO:0010834 IMP telomere maintenance via telomere shortening
GO:0032205 IMP negative regulation of telomere maintenance
GO:0033683 IDA nucleotide-excision repair, DNA incision
GO:0043566 IDA structure-specific DNA binding
GO:0047485 IPI protein N-terminus binding
GO:1901255 IBA nucleotide-excision repair involved in interstrand cross-link repair

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023206 Ercc4-001 protein_coding Mus_musculus 0 2163
ENSMUST00000129049 Ercc4-004 nonsense_mediated_decay Mus_musculus 0 1227
ENSMUST00000138527 Ercc4-002 retained_intron Mus_musculus 0 826
ENSMUST00000141024 Ercc4-003 nonsense_mediated_decay Mus_musculus 0 675

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