ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: CDC-like kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000176444 CLK2 9606 - 1:155262868-155278491 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355560 CLK2-003 155262874-155273482 protein_coding
  ENST00000361168 CLK2-002 155262868-155273287 protein_coding
  ENST00000368361 CLK2-001 155262868-155273516 protein_coding
  ENST00000471047 CLK2-006 155268094-155278491 processed_transcript
  ENST00000476983 CLK2-004 155262874-155273329 processed_transcript
  ENST00000484699 CLK2-007 155269166-155270841 processed_transcript
  ENST00000497188 CLK2-005 155262880-155269363 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000355560ENST00000361168ENST00000368361ENST00000476983ENST00000484699ENST00000497188
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000355560 N/A 1.087±0.00 N/A N/A 3.104±1.99
ENST00000361168 7.447±3.43 5.345±2.68 N/A 5.280±0.00 6.568±4.29
ENST00000368361 N/A 3.400±0.95 N/A N/A 3.522±1.17
ENST00000476983 N/A 3.937±1.47 16.080±0.00 10.607±0.00 7.565±10.37
ENST00000484699 N/A N/A N/A N/A 68.957±0.00
ENST00000497188 1.415±0.00 1.514±0.31 N/A 5.638±0.00 5.657±8.14

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0006468 IEA protein phosphorylation
GO:0010033 IEA response to organic substance
GO:0010212 IMP response to ionizing radiation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0032526 IEA response to retinoic acid
GO:0043484 IDA regulation of RNA splicing
GO:0045721 ISS negative regulation of gluconeogenesis
GO:0046777 ISS protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059870 clk2b protein_coding Danio_rerio
ENSDARG00000062954 clk2a protein_coding Danio_rerio
ENSMUSG00000068917 Clk2 protein_coding Mus_musculus

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