ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000068917 Clk2 10090 + 3:89164795-89176921 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000090927 Clk2-002 89164818-89176921 protein_coding
  ENSMUST00000121212 Clk2-001 89164795-89176921 protein_coding
  ENSMUST00000121931 Clk2-003 89164840-89176921 protein_coding
  ENSMUST00000128318 Clk2-005 89164979-89176921 nonsense_mediated_decay
  ENSMUST00000132830 Clk2-010 89173955-89175747 retained_intron
  ENSMUST00000133323 Clk2-009 89167164-89170409 retained_intron
  ENSMUST00000138822 Clk2-004 89164819-89176919 retained_intron
  ENSMUST00000139221 Clk2-011 89175035-89175971 processed_transcript
  ENSMUST00000148265 Clk2-008 89164819-89173457 protein_coding
  ENSMUST00000152205 Clk2-007 89164817-89167204 protein_coding
  ENSMUST00000153255 Clk2-006 89172165-89176080 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000090927ENSMUST00000121212ENSMUST00000121931ENSMUST00000128318ENSMUST00000133323ENSMUST00000138822ENSMUST00000148265
Transcript ID C166 Tie2+ EC mES
ENSMUST00000090927 1.956±0.00 2.506±0.00 4.509±0.00
ENSMUST00000121212 1.930±0.00 5.250±0.15 N/A
ENSMUST00000121931 7.262±1.98 6.172±2.78 6.896±0.02
ENSMUST00000128318 2.934±0.59 4.712±1.33 8.002±1.65
ENSMUST00000133323 N/A 5.694±0.00 N/A
ENSMUST00000138822 2.267±1.04 1.836±0.38 N/A
ENSMUST00000148265 N/A 8.341±1.48 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IDA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0006468 IDA protein phosphorylation
GO:0010033 IDA response to organic substance
GO:0010212 ISS response to ionizing radiation
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0032526 IDA response to retinoic acid
GO:0043484 ISS regulation of RNA splicing
GO:0045721 IMP negative regulation of gluconeogenesis
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059870 clk2b protein_coding Danio_rerio
ENSDARG00000062954 clk2a protein_coding Danio_rerio
ENSG00000176444 CLK2 CDC-like kinase 2 protein_coding Homo_sapiens

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