ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: TGFB-induced factor homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177426 TGIF1 9606 + 18:3411608-3459978 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330513 TGIF1-003 3451677-3458411 protein_coding
  ENST00000343820 TGIF1-002 3449704-3458411 protein_coding
  ENST00000345133 TGIF1-016 3451670-3458123 protein_coding
  ENST00000400167 TGIF1-201 3453774-3458406 protein_coding
  ENST00000401449 TGIF1-202 3411927-3458406 protein_coding
  ENST00000405385 TGIF1-203 3449651-3458406 protein_coding
  ENST00000407501 TGIF1-006 3449882-3458349 protein_coding
  ENST00000472042 TGIF1-004 3455414-3458411 protein_coding
  ENST00000546979 TGIF1-005 3450036-3457475 protein_coding
  ENST00000547233 TGIF1-009 3412204-3418846 retained_intron
  ENST00000548489 TGIF1-204 3412856-3458406 protein_coding
  ENST00000549253 TGIF1-012 3449413-3457456 protein_coding
  ENST00000549468 TGIF1-018 3453774-3457580 protein_coding
  ENST00000549546 TGIF1-017 3451724-3457918 protein_coding
  ENST00000549780 TGIF1-011 3448499-3457839 protein_coding
  ENST00000550958 TGIF1-010 3412854-3457574 protein_coding
  ENST00000551333 TGIF1-019 3455152-3457594 protein_coding
  ENST00000551402 TGIF1-007 3450177-3457113 protein_coding
  ENST00000551541 TGIF1-015 3451593-3457944 protein_coding
  ENST00000551557 TGIF1-013 3449537-3450040 processed_transcript
  ENST00000552383 TGIF1-008 3411608-3457684 protein_coding
  ENST00000577543 TGIF1-020 3450212-3457604 protein_coding
  ENST00000618001 TGIF1-001 3447609-3459978 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000330513ENST00000343820ENST00000345133ENST00000400167ENST00000405385ENST00000407501ENST00000472042ENST00000546979ENST00000549546ENST00000551541ENST00000577543
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000330513 N/A 1.827±0.83 N/A N/A 2.359±1.97
ENST00000343820 1.062±0.00 3.470±1.32 N/A 2.950±0.00 9.349±4.89
ENST00000345133 N/A 2.891±0.30 N/A 5.820±0.00 15.673±3.30
ENST00000400167 13.568±8.58 8.676±4.90 13.704±0.00 11.199±0.00 18.186±8.37
ENST00000405385 N/A N/A N/A N/A 8.088±0.00
ENST00000407501 N/A N/A N/A N/A 2.701±0.40
ENST00000472042 N/A 2.465±1.38 1.590±0.00 2.890±0.00 8.383±5.42
ENST00000546979 N/A N/A N/A N/A 17.739±10.82
ENST00000549546 N/A N/A N/A N/A 8.728±8.03
ENST00000551541 N/A 3.161±0.39 N/A N/A N/A
ENST00000577543 N/A 4.406±0.07 N/A N/A 23.754±4.08

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001843 IEA neural tube closure
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 TAS transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007275 TAS multicellular organismal development
GO:0007368 IEA determination of left/right symmetry
GO:0008285 IEA negative regulation of cell proliferation
GO:0009953 IEA dorsal/ventral pattern formation
GO:0010467 TAS gene expression
GO:0010470 IEA regulation of gastrulation
GO:0010629 IEA negative regulation of gene expression
GO:0038092 IEA nodal signaling pathway
GO:0042493 IEA response to drug
GO:0045666 IEA positive regulation of neuron differentiation
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0048387 IEA negative regulation of retinoic acid receptor signaling pathway
GO:0060041 IEA retina development in camera-type eye
GO:0070410 IEA co-SMAD binding
GO:0071363 IEA cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059337 tgif1 protein_coding Danio_rerio
ENSMUSG00000047407 Tgif1 protein_coding Mus_musculus

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