ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: euchromatic histone-lysine N-methyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000181090 EHMT1 9606 + 9:137618992-137870016 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371394 EHMT1-002 137619013-137792253 processed_transcript
  ENST00000460486 EHMT1-008 137667350-137717179 processed_transcript
  ENST00000460843 EHMT1-001 137619002-137836124 protein_coding
  ENST00000462484 EHMT1-004 137618992-137784393 protein_coding
  ENST00000462942 EHMT1-003 137744064-137870016 nonsense_mediated_decay
  ENST00000465566 EHMT1-011 137754231-137776781 processed_transcript
  ENST00000472849 EHMT1-017 137832632-137834992 processed_transcript
  ENST00000475564 EHMT1-006 137816341-137836117 retained_intron
  ENST00000475704 EHMT1-018 137834079-137835017 retained_intron
  ENST00000478940 EHMT1-010 137742966-137745602 processed_transcript
  ENST00000482340 EHMT1-013 137790833-137803199 processed_transcript
  ENST00000483653 EHMT1-016 137813491-137814827 retained_intron
  ENST00000486164 EHMT1-014 137790888-137813444 processed_transcript
  ENST00000488242 EHMT1-015 137800443-137814509 processed_transcript
  ENST00000492232 EHMT1-007 137667007-137717050 processed_transcript
  ENST00000493484 EHMT1-012 137788764-137802722 processed_transcript
  ENST00000494249 EHMT1-005 137815336-137835741 retained_intron
  ENST00000495657 EHMT1-009 137717095-137744019 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000460843ENST00000462484ENST00000488242ENST00000494249
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000460843 2.512±0.00 13.374±3.91 4.113±0.00 14.361±0.00 11.845±5.42
ENST00000462484 N/A N/A N/A N/A 1.793±0.86
ENST00000488242 N/A N/A N/A N/A 8.389±0.00
ENST00000494249 4.526±1.41 N/A 11.244±0.00 N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0002039 IPI p53 binding
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005694 IEA chromosome
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006306 ISS DNA methylation
GO:0008168 IDA methyltransferase activity
GO:0008270 IEA zinc ion binding
GO:0009790 ISS embryo development
GO:0016279 IDA protein-lysine N-methyltransferase activity
GO:0016568 IDA chromatin modification
GO:0016571 IDA histone methylation
GO:0018024 IDA:IEA histone-lysine N-methyltransferase activity
GO:0018026 ISS peptidyl-lysine monomethylation
GO:0018027 IDA peptidyl-lysine dimethylation
GO:0034968 IEA histone lysine methylation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0046974 ISS histone methyltransferase activity (H3-K9 specific)
GO:0046976 ISS histone methyltransferase activity (H3-K27 specific)
GO:0051567 IEA histone H3-K9 methylation
GO:0070734 IEA histone H3-K27 methylation
GO:0070742 IEA C2H2 zinc finger domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026634 ehmt1b protein_coding Danio_rerio
ENSDARG00000068157 ehmt1a protein_coding Danio_rerio
ENSMUSG00000036893 Ehmt1 protein_coding Mus_musculus

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