ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185033 SEMA4B 9606 + 15:90160604-90229679 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332496 SEMA4B-002 90184963-90229670 protein_coding
  ENST00000411539 SEMA4B-001 90201319-90229676 protein_coding
  ENST00000558051 SEMA4B-014 90201536-90221392 processed_transcript
  ENST00000558065 SEMA4B-004 90219208-90229679 retained_intron
  ENST00000558848 SEMA4B-012 90217617-90220218 retained_intron
  ENST00000558895 SEMA4B-007 90190344-90217554 protein_coding
  ENST00000558975 SEMA4B-015 90221618-90223792 retained_intron
  ENST00000559074 SEMA4B-005 90221750-90229660 protein_coding
  ENST00000559247 SEMA4B-019 90225324-90228407 protein_coding
  ENST00000559300 SEMA4B-011 90184918-90219843 nonsense_mediated_decay
  ENST00000559322 SEMA4B-006 90160604-90217786 protein_coding
  ENST00000559792 SEMA4B-009 90191928-90217810 protein_coding
  ENST00000559983 SEMA4B-017 90225072-90228155 protein_coding
  ENST00000560003 SEMA4B-013 90217056-90217785 retained_intron
  ENST00000560089 SEMA4B-003 90201421-90228747 nonsense_mediated_decay
  ENST00000560263 SEMA4B-008 90191922-90193563 processed_transcript
  ENST00000560993 SEMA4B-016 90223877-90225674 retained_intron
  ENST00000561085 SEMA4B-010 90184920-90221075 protein_coding
  ENST00000561252 SEMA4B-018 90225002-90225608 retained_intron
  ENST00000561321 SEMA4B-020 90227239-90228062 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000332496ENST00000411539ENST00000558065ENST00000559074ENST00000560089
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000332496 N/A 2.793±1.73 N/A N/A 0.432±0.24
ENST00000411539 0.706±0.00 4.189±1.73 N/A 8.071±0.00 4.629±3.96
ENST00000558065 N/A N/A N/A N/A 0.029±0.00
ENST00000559074 N/A 5.063±1.18 1.335±0.00 2.835±0.00 0.944±0.10
ENST00000560089 N/A N/A N/A N/A 1.168±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00079J CIL_00079J_0001 CGP
CIL_0008FE CIL_0008FE_0001 VISTA
CIL_0000SV CIL_0000SV_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 IEA receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0007275 IEA multicellular organismal development
GO:0007399 IEA nervous system development
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030154 IEA cell differentiation
GO:0045202 IEA synapse

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074414 sema4ba protein_coding Danio_rerio
ENSDARG00000076104 SEMA4B (2 of 2) protein_coding Danio_rerio
ENSMUSG00000030539 Sema4b protein_coding Mus_musculus

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