ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: phospholipase C, delta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000187091 PLCD1 9606 - 3:38007496-38029762 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000334661 PLCD1-001 38007498-38029762 protein_coding
  ENST00000417185 PLCD1-004 38007496-38008335 retained_intron
  ENST00000461445 PLCD1-005 38007496-38029559 retained_intron
  ENST00000463876 PLCD1-006 38007498-38024787 protein_coding
  ENST00000473834 PLCD1-009 38020229-38024576 processed_transcript
  ENST00000479619 PLCD1-010 38011293-38019034 processed_transcript
  ENST00000484829 PLCD1-011 38008463-38010422 retained_intron
  ENST00000495367 PLCD1-012 38008578-38009883 retained_intron
  ENST00000495395 PLCD1-013 38008274-38008764 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000334661ENST00000417185ENST00000461445ENST00000463876ENST00000479619ENST00000484829
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000334661 0.929±0.00 16.716±15.92 1.322±0.00 0.719±0.00 2.497±1.99
ENST00000417185 8.640±0.63 24.138±19.32 13.675±0.00 N/A 1.952±0.01
ENST00000461445 N/A N/A 0.770±0.00 N/A 0.196±0.02
ENST00000463876 1.143±0.00 5.313±4.80 N/A 0.817±0.00 1.976±1.62
ENST00000479619 N/A 28.861±24.01 N/A 3.043±0.00 N/A
ENST00000484829 1.724±0.00 2.714±0.00 2.745±0.00 1.341±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008CZ CIL_0008CZ_0001 VISTA
CIL_00099X CIL_00099X_0001 VISTA
CIL_0005A4 CIL_0005A4_0001 CGP
CIL_0005VD CIL_0005VD_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001786 IEA phosphatidylserine binding
GO:0004435 IEA phosphatidylinositol phospholipase C activity
GO:0004629 IEA phospholipase C activity
GO:0004871 IEA signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005829 IEA cytosol
GO:0005886 TAS plasma membrane
GO:0006629 IEA lipid metabolic process
GO:0006644 TAS phospholipid metabolic process
GO:0007165 IEA signal transduction
GO:0008081 IEA phosphoric diester hydrolase activity
GO:0016042 IEA lipid catabolic process
GO:0032794 IPI GTPase activating protein binding
GO:0035556 IEA intracellular signal transduction
GO:0042127 IEA regulation of cell proliferation
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0060716 IEA labyrinthine layer blood vessel development
GO:0070062 IDA extracellular vesicular exosome
GO:0070300 IEA phosphatidic acid binding
GO:1901981 IEA phosphatidylinositol phosphate binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034080 plcd1b protein_coding Danio_rerio
ENSDARG00000059123 plcd1a protein_coding Danio_rerio
ENSMUSG00000010660 Plcd1 protein_coding Mus_musculus

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