ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sirtuin 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000187531 SIRT7 9606 - 17:81911939-81921323 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000328666 SIRT7-001 81911939-81918194 protein_coding
  ENST00000536038 SIRT7-002 81911939-81918176 retained_intron
  ENST00000570367 SIRT7-011 81915256-81918152 retained_intron
  ENST00000571213 SIRT7-016 81917363-81918116 retained_intron
  ENST00000571233 SIRT7-021 81914052-81914726 retained_intron
  ENST00000571832 SIRT7-004 81911939-81918152 retained_intron
  ENST00000571915 SIRT7-019 81914389-81915971 retained_intron
  ENST00000572350 SIRT7-017 81914135-81917814 retained_intron
  ENST00000572671 SIRT7-014 81915336-81918132 retained_intron
  ENST00000572902 SIRT7-008 81914087-81921323 protein_coding
  ENST00000572976 SIRT7-006 81911939-81917153 retained_intron
  ENST00000573367 SIRT7-015 81914368-81918132 retained_intron
  ENST00000573576 SIRT7-012 81917365-81918148 retained_intron
  ENST00000574153 SIRT7-023 81913577-81914250 retained_intron
  ENST00000574495 SIRT7-009 81914294-81918162 retained_intron
  ENST00000574915 SIRT7-010 81917768-81918153 retained_intron
  ENST00000574992 SIRT7-007 81911939-81916452 retained_intron
  ENST00000575244 SIRT7-020 81914966-81915926 retained_intron
  ENST00000575360 SIRT7-013 81914443-81918136 nonsense_mediated_decay
  ENST00000576156 SIRT7-022 81913774-81914691 retained_intron
  ENST00000577065 SIRT7-018 81914193-81917780 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000328666ENST00000571832ENST00000575244
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000328666 20.359±0.50 15.851±7.86 20.347±0.00 8.071±0.00 10.348±4.46
ENST00000571832 N/A 1.705±0.02 N/A N/A 1.222±0.00
ENST00000575244 N/A N/A N/A N/A 0.419±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004LV CIL_0004LV_0001 CGP
CIL_0004LW CIL_0004LW_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005730 IDA nucleolus
GO:0005731 IDA nucleolus organizer region
GO:0005737 IEA cytoplasm
GO:0007072 IMP positive regulation of transcription on exit from mitosis
GO:0009303 IMP rRNA transcription
GO:0046872 IEA metal ion binding
GO:0070403 IEA NAD+ binding
GO:0070932 IDA histone H3 deacetylation
GO:0070933 IDA histone H4 deacetylation
GO:0097372 IDA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060645 sirt7 protein_coding Danio_rerio
ENSMUSG00000025138 Sirt7 protein_coding Mus_musculus

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