ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025138 Sirt7 10090 - 11:120618372-120625240 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000080202 Sirt7-001 120618372-120625014 protein_coding
  ENSMUST00000106183 Sirt7-002 120623990-120624984 protein_coding
  ENSMUST00000127882 Sirt7-006 120618372-120625240 retained_intron
  ENSMUST00000130743 Sirt7-009 120621990-120622802 retained_intron
  ENSMUST00000133625 Sirt7-011 120618374-120624999 retained_intron
  ENSMUST00000134255 Sirt7-005 120618388-120625020 retained_intron
  ENSMUST00000146809 Sirt7-003 120618420-120620977 protein_coding
  ENSMUST00000152331 Sirt7-010 120620999-120624990 processed_transcript
  ENSMUST00000153018 Sirt7-007 120623280-120624992 retained_intron
  ENSMUST00000153532 Sirt7-008 120618372-120624969 retained_intron
  ENSMUST00000154714 Sirt7-004 120618769-120619369 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000080202ENSMUST00000146809
Transcript ID C166 Tie2+ EC mES
ENSMUST00000080202 13.595±0.19 15.240±10.81 4.247±0.30
ENSMUST00000146809 N/A 11.710±3.85 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004LV CIL_0004LV_0002 CGP
CIL_0004LW CIL_0004LW_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0003682 ISS chromatin binding
GO:0005515 IEA protein binding
GO:0005730 ISS nucleolus
GO:0005731 ISS nucleolus organizer region
GO:0005737 IEA cytoplasm
GO:0007072 ISS positive regulation of transcription on exit from mitosis
GO:0009303 ISS rRNA transcription
GO:0046872 IEA metal ion binding
GO:0070403 IEA NAD+ binding
GO:0070932 ISS histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0097372 ISS NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060645 sirt7 protein_coding Danio_rerio
ENSG00000187531 SIRT7 sirtuin 7 protein_coding Homo_sapiens

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