ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: neighbor of BRCA1 gene 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188554 NBR1 9606 + 17:43170481-43211689 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341165 NBR1-001 43170481-43211689 protein_coding
  ENST00000422280 NBR1-201 43170494-43211687 protein_coding
  ENST00000542611 NBR1-002 43171202-43209993 protein_coding
  ENST00000585505 NBR1-005 43189914-43196120 retained_intron
  ENST00000586650 NBR1-007 43170494-43177960 protein_coding
  ENST00000589872 NBR1-004 43171243-43209857 protein_coding
  ENST00000590996 NBR1-003 43171214-43210521 protein_coding
  ENST00000592304 NBR1-006 43171225-43176676 retained_intron
  ENST00000617399 NBR1-202 43177936-43177998 misc_RNA

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000341165ENST00000422280ENST00000542611ENST00000585505ENST00000590996
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000341165 11.824±4.17 10.234±0.00 11.892±8.59
ENST00000422280 1.442±0.00 N/A 1.632±0.88
ENST00000542611 N/A N/A 2.335±1.74
ENST00000585505 N/A N/A 0.490±0.08
ENST00000590996 6.791±2.04 7.605±0.00 7.640±4.75

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00040M CIL_00040M_0001 CGP
CIL_0000KX CIL_0000KX_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000407 IEA pre-autophagosomal structure
GO:0005515 IPI:IEA protein binding
GO:0005764 IEA lysosome
GO:0005770 ISS late endosome
GO:0005776 ISS autophagic vacuole
GO:0005829 IDA cytosol
GO:0008270 IEA zinc ion binding
GO:0016020 IDA membrane
GO:0016236 IDA macroautophagy
GO:0030500 ISS regulation of bone mineralization
GO:0031410 IEA cytoplasmic vesicle
GO:0032872 ISS regulation of stress-activated MAPK cascade
GO:0043130 IDA ubiquitin binding
GO:0045668 ISS negative regulation of osteoblast differentiation
GO:0051019 ISS mitogen-activated protein kinase binding
GO:0051259 IDA protein oligomerization
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077297 nbr1 protein_coding Danio_rerio
ENSDARG00000078772 NBR1 (2 of 2) protein_coding Danio_rerio
ENSMUSG00000017119 Nbr1 protein_coding Mus_musculus

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