ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: nuclear receptor corepressor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196498 NCOR2 9606 - 12:124324415-124567589 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356219 NCOR2-201 124324416-124422554 protein_coding
  ENST00000404121 NCOR2-202 124324416-124422554 protein_coding
  ENST00000404621 NCOR2-002 124324415-124535603 protein_coding
  ENST00000405201 NCOR2-005 124324415-124495252 protein_coding
  ENST00000413172 NCOR2-018 124325420-124327585 protein_coding
  ENST00000418829 NCOR2-017 124325380-124332345 protein_coding
  ENST00000420698 NCOR2-004 124419959-124518294 protein_coding
  ENST00000429285 NCOR2-001 124324598-124535603 protein_coding
  ENST00000440187 NCOR2-013 124337104-124341863 protein_coding
  ENST00000440337 NCOR2-015 124328532-124333256 protein_coding
  ENST00000443451 NCOR2-022 124325386-124334646 retained_intron
  ENST00000448008 NCOR2-019 124430641-124483769 protein_coding
  ENST00000448614 NCOR2-009 124372460-124388824 protein_coding
  ENST00000453428 NCOR2-012 124340007-124342055 protein_coding
  ENST00000458234 NCOR2-003 124346593-124567464 protein_coding
  ENST00000461081 NCOR2-006 124331475-124336392 retained_intron
  ENST00000464377 NCOR2-016 124326123-124327659 retained_intron
  ENST00000473999 NCOR2-011 124347402-124348940 retained_intron
  ENST00000474079 NCOR2-014 124334344-124335181 retained_intron
  ENST00000493859 NCOR2-010 124355059-124356685 retained_intron
  ENST00000494460 NCOR2-007 124429395-124430641 retained_intron
  ENST00000536195 NCOR2-020 124354837-124356850 retained_intron
  ENST00000542565 NCOR2-008 124486374-124567589 retained_intron
  ENST00000542927 NCOR2-024 124430610-124483774 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000356219ENST00000404121ENST00000404621ENST00000405201ENST00000420698ENST00000458234
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000356219 N/A N/A N/A N/A 6.706±2.95
ENST00000404121 2.928±0.00 6.024±0.00 2.778±0.00 N/A 11.226±4.36
ENST00000404621 N/A 14.081±5.90 N/A 8.395±0.00 10.159±7.41
ENST00000405201 N/A 10.479±5.02 N/A N/A 8.510±4.56
ENST00000420698 N/A 3.167±0.00 N/A N/A N/A
ENST00000458234 N/A 3.418±1.42 N/A 4.030±0.00 1.865±1.66

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000399 CIL_000399_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IEA histone deacetylase complex
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0001012 IEA RNA polymerase II regulatory region DNA binding
GO:0001701 IEA in utero embryonic development
GO:0003007 IEA heart morphogenesis
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003714 IMP transcription corepressor activity
GO:0005112 IPI Notch binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0007595 IEA lactation
GO:0010243 IEA response to organonitrogen compound
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016363 IDA nuclear matrix
GO:0016604 IDA nuclear body
GO:0016922 IEA ligand-dependent nuclear receptor binding
GO:0017053 IDA transcriptional repressor complex
GO:0021537 IEA telencephalon development
GO:0021846 IEA cell proliferation in forebrain
GO:0030900 IEA forebrain development
GO:0032355 IEA response to estradiol
GO:0032403 IEA protein complex binding
GO:0035259 IEA glucocorticoid receptor binding
GO:0042593 IEA glucose homeostasis
GO:0042698 IEA ovulation cycle
GO:0042826 IPI histone deacetylase binding
GO:0042974 IEA retinoic acid receptor binding
GO:0043565 IEA sequence-specific DNA binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045599 IEA negative regulation of fat cell differentiation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046965 IEA retinoid X receptor binding
GO:0047485 IPI protein N-terminus binding
GO:0050872 IEA white fat cell differentiation
GO:0060206 IEA estrous cycle phase
GO:0060509 IEA Type I pneumocyte differentiation
GO:0072365 IMP regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000966 ncor2 protein_coding Danio_rerio
ENSMUSG00000029478 Ncor2 protein_coding Mus_musculus

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