ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196781 TLE1 9606 - 9:81583683-81689305 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376463 TLE1-005 81633469-81687368 protein_coding
  ENST00000376472 TLE1-201 81584184-81688266 protein_coding
  ENST00000376484 TLE1-004 81599865-81613522 protein_coding
  ENST00000376499 TLE1-001 81583683-81689305 protein_coding
  ENST00000418319 TLE1-002 81620454-81688448 protein_coding
  ENST00000464999 TLE1-003 81611843-81620539 processed_transcript
  ENST00000491534 TLE1-006 81611806-81620557 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000376463ENST00000376472ENST00000376499ENST00000418319
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000376463 7.382±0.00 7.027±0.90 6.661±0.00 10.077±0.00 10.351±4.89
ENST00000376472 N/A N/A N/A N/A 5.047±3.46
ENST00000376499 5.913±1.15 5.583±1.96 1.084±0.00 5.063±0.00 8.524±5.45
ENST00000418319 N/A N/A N/A N/A 4.012±0.14

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007KE CIL_0007KE_0002 UCNEbase
CIL_00090V CIL_00090V_0001 VISTA
CIL_0008X3 CIL_0008X3_0001 VISTA
CIL_0009AO CIL_0009AO_0001 VISTA
CIL_0008C4 CIL_0008C4_0001 VISTA
CIL_0008TV CIL_0008TV_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001106 IDA RNA polymerase II transcription corepressor activity
GO:0003682 IEA chromatin binding
GO:0003714 IEA transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 IMP cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0007165 TAS signal transduction
GO:0007219 TAS Notch signaling pathway
GO:0007275 TAS multicellular organismal development
GO:0008134 IPI transcription factor binding
GO:0009887 TAS organ morphogenesis
GO:0010628 IMP positive regulation of gene expression
GO:0016055 IEA Wnt signaling pathway
GO:0030178 NAS negative regulation of Wnt signaling pathway
GO:0042802 IPI identical protein binding
GO:0043124 IDA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:2000811 IMP negative regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067832 AES (3 of 3) protein_coding Danio_rerio
ENSMUSG00000008305 Tle1 protein_coding Mus_musculus

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