ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info

Description: transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000376499 TLE1-001 ENSG00000196781 9606 - 9:81583683-81689305 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000376499
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000376499 5.913±1.15 5.583±1.96 1.084±0.00 5.063±0.00 8.524±5.45

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001106 IDA RNA polymerase II transcription corepressor activity
GO:0003682 IEA chromatin binding
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 IMP cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0007165 TAS signal transduction
GO:0007219 TAS Notch signaling pathway
GO:0007275 TAS multicellular organismal development
GO:0008134 IPI transcription factor binding
GO:0009887 TAS organ morphogenesis
GO:0010628 IMP positive regulation of gene expression
GO:0016055 IEA Wnt signaling pathway
GO:0030178 NAS negative regulation of Wnt signaling pathway
GO:0042802 IPI identical protein binding
GO:0043124 IDA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:2000811 IMP negative regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000072695 Tle1-001 protein_coding Mus_musculus 0 3140
ENSMUST00000074216 Tle1-201 protein_coding Mus_musculus 0 3118
ENSMUST00000102848 Tle1-006 protein_coding Mus_musculus 0 3022
ENSMUST00000132550 Tle1-005 retained_intron Mus_musculus 0 2867
ENSMUST00000030095 Tle1-008 protein_coding Mus_musculus 0 2427
ENSMUST00000052011 Tle4-201 protein_coding Mus_musculus 0 1463
ENSMUST00000167776 Tle4-202 protein_coding Mus_musculus 0 1245
ENSMUST00000159050 Tle3-007 protein_coding Mus_musculus 0 1061
ENSMUST00000107337 Tle1-002 protein_coding Mus_musculus 0 1002
ENSMUST00000162127 Tle3-009 protein_coding Mus_musculus 0 911
ENSMUST00000034820 Tle3-002 protein_coding Mus_musculus 0 911
ENSMUST00000178113 Tle3-201 protein_coding Mus_musculus 0 894
ENSMUST00000159386 Tle3-008 protein_coding Mus_musculus 0 894
ENSMUST00000161207 Tle3-006 protein_coding Mus_musculus 0 894
ENSMUST00000162583 Tle3-005 protein_coding Mus_musculus 0 894
ENSMUST00000161689 Tle3-011 protein_coding Mus_musculus 0 894
ENSMUST00000159630 Tle3-010 protein_coding Mus_musculus 0 894
ENSMUST00000160882 Tle3-003 protein_coding Mus_musculus 0 894
ENSMUST00000162973 Tle3-001 protein_coding Mus_musculus 0 894
ENSMUST00000159140 Tle3-012 retained_intron Mus_musculus 0 878
ENSDART00000130553 tle3b-001 protein_coding Danio_rerio 0 850
ENSMUST00000137075 Tle1-007 protein_coding Mus_musculus 0 793
ENSMUST00000134225 Tle1-004 processed_transcript Mus_musculus 0 689
ENSMUST00000123259 Tle1-009 processed_transcript Mus_musculus 0 470

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