ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: adaptor-related protein complex 2, alpha 1 subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196961 AP2A1 9606 + 19:49766968-49807113 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354293 AP2A1-001 49766968-49807112 protein_coding
  ENST00000359032 AP2A1-008 49767134-49807110 protein_coding
  ENST00000593788 AP2A1-007 49800692-49801733 retained_intron
  ENST00000594838 AP2A1-009 49802522-49805933 retained_intron
  ENST00000597774 AP2A1-004 49767136-49806791 nonsense_mediated_decay
  ENST00000600199 AP2A1-010 49767007-49797562 processed_transcript
  ENST00000600466 AP2A1-003 49801547-49804540 retained_intron
  ENST00000601356 AP2A1-002 49804876-49807113 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000354293ENST00000359032ENST00000594838ENST00000597774ENST00000600199ENST00000601356
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000354293 13.489±0.00 59.843±42.06 7.675±0.00 49.206±0.00 39.011±33.93
ENST00000359032 N/A 29.017±9.16 N/A N/A N/A
ENST00000594838 79.578±0.00 N/A N/A N/A N/A
ENST00000597774 N/A 26.312±10.18 N/A N/A N/A
ENST00000600199 N/A N/A N/A N/A 2.185±1.72
ENST00000601356 N/A N/A 7.858±0.00 N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006886 NAS:IEA intracellular protein transport
GO:0006895 NAS Golgi to endosome transport
GO:0006897 NAS endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008022 IEA protein C-terminus binding
GO:0008565 IEA protein transporter activity
GO:0015031 IEA protein transport
GO:0016020 IDA:IEA membrane
GO:0016032 TAS viral process
GO:0016192 IEA vesicle-mediated transport
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 ISS protein kinase binding
GO:0030117 IEA membrane coat
GO:0030122 NAS AP-2 adaptor complex
GO:0030130 NAS clathrin coat of trans-Golgi network vesicle
GO:0030131 IEA clathrin adaptor complex
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0043234 IEA protein complex
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050690 TAS regulation of defense response to virus by virus
GO:1900126 IMP negative regulation of hyaluronan biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054320 ap2a1 protein_coding Danio_rerio
ENSMUSG00000060279 Ap2a1 protein_coding Mus_musculus

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