ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000060279 Ap2a1 10090 - 7:44900373-44929496 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000085399 Ap2a1-201 44900374-44929490 protein_coding
  ENSMUST00000107857 Ap2a1-002 44900385-44929426 protein_coding
  ENSMUST00000164575 Ap2a1-004 44906114-44909829 nonsense_mediated_decay
  ENSMUST00000165890 Ap2a1-008 44900992-44903884 protein_coding
  ENSMUST00000166060 Ap2a1-007 44915833-44929462 retained_intron
  ENSMUST00000166972 Ap2a1-001 44900373-44929496 protein_coding
  ENSMUST00000167675 Ap2a1-006 44916250-44916734 retained_intron
  ENSMUST00000167930 Ap2a1-202 44900374-44929490 protein_coding
  ENSMUST00000168862 Ap2a1-003 44916243-44929466 nonsense_mediated_decay
  ENSMUST00000169527 Ap2a1-005 44916019-44928643 processed_transcript
  ENSMUST00000170656 Ap2a1-009 44900716-44901694 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000107857ENSMUST00000166972ENSMUST00000167930
Transcript ID C166 Tie2+ EC mES
ENSMUST00000107857 32.495±1.54 24.230±19.61 9.323±2.91
ENSMUST00000166972 N/A N/A 6.601±0.00
ENSMUST00000167930 N/A 2.241±0.00 7.920±2.49

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005905 IEA coated pit
GO:0006886 TAS intracellular protein transport
GO:0006897 IEA endocytosis
GO:0008022 IEA protein C-terminus binding
GO:0008565 IEA protein transporter activity
GO:0016192 TAS vesicle-mediated transport
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0019901 IPI protein kinase binding
GO:0030117 IDA membrane coat
GO:0030131 IEA clathrin adaptor complex
GO:0030141 TAS secretory granule
GO:0043234 IEA protein complex
GO:1900126 ISS negative regulation of hyaluronan biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054320 ap2a1 protein_coding Danio_rerio
ENSG00000196961 AP2A1 adaptor-related protein complex 2, alpha 1 subunit protein_coding Homo_sapiens

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