ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: myosin, heavy chain 6, cardiac muscle, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197616 MYH6 9606 - 14:23381990-23408277 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356287 MYH6-001 23382019-23407592 protein_coding
  ENST00000405093 MYH6-201 23381990-23408277 protein_coding
  ENST00000557461 MYH6-002 23399712-23407616 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHUVECENST00000356287
Transcript ID HAoEC HHSEC HUVEC
ENST00000356287 0.008±0.01 0.202±0.00 0.012±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00090C CIL_00090C_0001 VISTA
CIL_0009BW CIL_0009BW_0001 VISTA
CIL_0008Q4 CIL_0008Q4_0001 VISTA
CIL_0008QH CIL_0008QH_0001 VISTA
CIL_00051L CIL_00051L_0001 CGP
CIL_0004Z7 CIL_0004Z7_0007 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000146 ISS microfilament motor activity
GO:0001701 ISS in utero embryonic development
GO:0001725 IEA stress fiber
GO:0002026 ISS regulation of the force of heart contraction
GO:0002027 IDA regulation of heart rate
GO:0003774 IEA motor activity
GO:0003779 IEA actin binding
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005859 TAS muscle myosin complex
GO:0005925 IDA focal adhesion
GO:0006200 IDA ATP catabolic process
GO:0006936 IDA muscle contraction
GO:0006941 ISS striated muscle contraction
GO:0007512 IMP adult heart development
GO:0007522 ISS visceral muscle development
GO:0008016 ISS regulation of heart contraction
GO:0008217 ISS regulation of blood pressure
GO:0016459 TAS:IEA myosin complex
GO:0016887 IDA ATPase activity
GO:0019901 IPI protein kinase binding
GO:0030016 ISS myofibril
GO:0030017 TAS sarcomere
GO:0030018 IEA Z disc
GO:0030048 IEA actin filament-based movement
GO:0030049 IMP muscle filament sliding
GO:0030239 ISS myofibril assembly
GO:0030509 IEA BMP signaling pathway
GO:0030898 IMP actin-dependent ATPase activity
GO:0032982 IEA myosin filament
GO:0043462 ISS regulation of ATPase activity
GO:0045214 ISS sarcomere organization
GO:0048739 ISS cardiac muscle fiber development
GO:0055009 IMP atrial cardiac muscle tissue morphogenesis
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060420 IEA regulation of heart growth

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079564 vmhc protein_coding Danio_rerio
ENSDARG00000079782 vmhcl protein_coding Danio_rerio
ENSMUSG00000040752 Myh6 protein_coding Mus_musculus

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