ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: calcium channel, voltage-dependent, R type, alpha 1E subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198216 CACNA1E 9606 + 1:181413102-181808084 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357570 CACNA1E-201 181483745-181798959 protein_coding
  ENST00000358338 CACNA1E-202 181483745-181806778 protein_coding
  ENST00000360108 CACNA1E-006 181483738-181798912 protein_coding
  ENST00000367567 CACNA1E-203 181483745-181806778 protein_coding
  ENST00000367570 CACNA1E-001 181483580-181801580 protein_coding
  ENST00000367573 CACNA1E-003 181483745-181798959 protein_coding
  ENST00000524607 CACNA1E-004 181413102-181716129 protein_coding
  ENST00000533229 CACNA1E-005 181483311-181652094 retained_intron
  ENST00000621551 CACNA1E-204 181483745-181806778 protein_coding
  ENST00000621791 CACNA1E-002 181483580-181808084 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000360108ENST00000367570ENST00000524607ENST00000533229
Transcript ID BECs HAoEC HUVEC
ENST00000360108 0.012±0.00 0.006±0.00 0.006±0.00
ENST00000367570 N/A N/A 0.002±0.00
ENST00000524607 0.046±0.00 0.019±0.00 0.001±0.00
ENST00000533229 N/A 0.030±0.00 0.009±0.01

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007W1 CIL_0007W1_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005245 IEA voltage-gated calcium channel activity
GO:0005509 IEA calcium ion binding
GO:0005886 IBA plasma membrane
GO:0005891 IEA voltage-gated calcium channel complex
GO:0006112 TAS energy reserve metabolic process
GO:0006810 TAS transport
GO:0006811 IEA ion transport
GO:0007268 IBA synaptic transmission
GO:0008331 IBA high voltage-gated calcium channel activity
GO:0016020 IEA membrane
GO:0034765 IEA regulation of ion transmembrane transport
GO:0044281 TAS small molecule metabolic process
GO:0050796 TAS regulation of insulin secretion
GO:0051899 TAS membrane depolarization
GO:0055085 IEA transmembrane transport
GO:0070509 IBA calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062346 cacna1ea protein_coding Danio_rerio
ENSDARG00000095614 cacna1eb protein_coding Danio_rerio
ENSMUSG00000004110 Cacna1e protein_coding Mus_musculus

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