ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: phosphatase and actin regulator 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204138 PHACTR4 9606 + 1:28369603-28500369 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000373836 PHACTR4-004 28438171-28500308 protein_coding
  ENST00000373839 PHACTR4-001 28369603-28500369 protein_coding
  ENST00000463428 PHACTR4-003 28369739-28467241 processed_transcript
  ENST00000493669 PHACTR4-002 28369744-28497156 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000373836ENST00000373839ENST00000493669
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000373836 2.221±0.00 5.051±1.30 N/A 5.997±0.00 2.847±1.72
ENST00000373839 0.461±0.00 2.315±1.02 0.610±0.00 3.326±0.00 4.573±2.97
ENST00000493669 N/A 4.819±0.89 N/A N/A 2.336±1.29

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001755 ISS neural crest cell migration
GO:0001843 ISS neural tube closure
GO:0003779 ISS actin binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0007266 ISS Rho protein signal transduction
GO:0008157 ISS protein phosphatase 1 binding
GO:0030027 ISS lamellipodium
GO:0030036 ISS actin cytoskeleton organization
GO:0043085 ISS positive regulation of catalytic activity
GO:0048484 ISS enteric nervous system development
GO:0051726 ISS regulation of cell cycle
GO:0061386 ISS closure of optic fissure
GO:0071862 ISS protein phosphatase type 1 activator activity
GO:2001045 ISS negative regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015552 phactr4a protein_coding Danio_rerio
ENSDARG00000032221 phactr4b protein_coding Danio_rerio
ENSMUSG00000066043 Phactr4 protein_coding Mus_musculus

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