ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000066043 Phactr4 10090 - 4:132355923-132422489 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000084170 Phactr4-201 132355930-132422446 protein_coding
  ENSMUST00000084249 Phactr4-002 132358249-132398211 protein_coding
  ENSMUST00000102568 Phactr4-001 132355923-132422489 protein_coding
  ENSMUST00000127516 Phactr4-005 132360677-132370531 processed_transcript
  ENSMUST00000136711 Phactr4-004 132377461-132398199 protein_coding
  ENSMUST00000152271 Phactr4-003 132370951-132422441 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000084170ENSMUST00000102568
Transcript ID C166 Tie2+ EC mES
ENSMUST00000084170 5.305±0.58 5.885±2.96 6.241±1.72
ENSMUST00000102568 6.907±0.89 3.230±1.14 7.502±1.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00099N CIL_00099N_0002 VISTA
CIL_0001RA CIL_0001RA_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001755 IMP neural crest cell migration
GO:0001843 IMP neural tube closure
GO:0003779 IDA actin binding
GO:0004864 IEA protein phosphatase inhibitor activity
GO:0005622 IMP intracellular
GO:0005737 IEA cytoplasm
GO:0007266 IMP Rho protein signal transduction
GO:0008157 IDA protein phosphatase 1 binding
GO:0030027 IDA lamellipodium
GO:0030036 IMP actin cytoskeleton organization
GO:0043085 IDA positive regulation of catalytic activity
GO:0043086 IEA negative regulation of catalytic activity
GO:0048484 IMP enteric nervous system development
GO:0051726 IMP regulation of cell cycle
GO:0061386 IMP closure of optic fissure
GO:0071862 IDA protein phosphatase type 1 activator activity
GO:2001045 IMP negative regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015552 phactr4a protein_coding Danio_rerio
ENSDARG00000032221 phactr4b protein_coding Danio_rerio
ENSG00000204138 PHACTR4 phosphatase and actin regulator 4 protein_coding Homo_sapiens

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