ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: FGFR1 oncogene partner
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213066 FGFR1OP 9606 + 6:166999182-167052713 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000349556 FGFR1OP-002 166999408-167040317 protein_coding
  ENST00000366847 FGFR1OP-001 166999182-167052713 protein_coding
  ENST00000476078 FGFR1OP-004 166999617-167004304 processed_transcript
  ENST00000488525 FGFR1OP-006 167024790-167033882 processed_transcript
  ENST00000494781 FGFR1OP-003 166999457-167011691 processed_transcript
  ENST00000496181 FGFR1OP-005 167022426-167025211 processed_transcript
  ENST00000622353 FGFR1OP-201 166999317-167042418 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000349556ENST00000366847ENST00000488525ENST00000622353
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000349556 2.062±0.87 4.126±0.86 1.865±0.00 4.051±0.00 3.729±2.21
ENST00000366847 0.128±0.02 0.098±0.02 0.158±0.00 N/A 0.156±0.08
ENST00000488525 9.171±0.00 N/A N/A N/A N/A
ENST00000622353 1.485±0.27 0.764±0.37 2.927±0.00 2.576±0.00 2.593±2.06

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004W6 CIL_0004W6_0001 CGP
CIL_0002HA CIL_0002HA_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0004713 TAS protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005813 IDA centrosome
GO:0005815 IEA microtubule organizing center
GO:0005829 TAS cytosol
GO:0006469 IDA negative regulation of protein kinase activity
GO:0008284 IDA positive regulation of cell proliferation
GO:0018108 TAS peptidyl-tyrosine phosphorylation
GO:0019901 IPI protein kinase binding
GO:0030292 IDA protein tyrosine kinase inhibitor activity
GO:0030307 IDA positive regulation of cell growth
GO:0030335 IDA positive regulation of cell migration
GO:0034453 IEA microtubule anchoring
GO:0042803 IDA protein homodimerization activity
GO:0048471 IDA perinuclear region of cytoplasm
GO:0061099 IDA negative regulation of protein tyrosine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003058 fgfr1op protein_coding Danio_rerio
ENSMUSG00000069135 Fgfr1op protein_coding Mus_musculus

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