ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: OTU deubiquitinase 7B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000264522 OTUD7B 9606 - 1:149937812-150010676 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000417191 OTUD7B-003 149947291-150010675 protein_coding
  ENST00000581312 OTUD7B-001 149937812-150010676 protein_coding
  ENST00000619871 OTUD7B-002 149960927-149971261 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000417191ENST00000581312
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000417191 N/A 4.314±0.75 N/A 2.342±0.98
ENST00000581312 0.178±0.00 2.018±0.84 1.821±0.00 1.598±0.80

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0002385 ISS mucosal immune response
GO:0003677 IEA DNA binding
GO:0004221 ISS ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006508 IEA proteolysis
GO:0008234 ISS cysteine-type peptidase activity
GO:0008270 IEA zinc ion binding
GO:0016579 IEA protein deubiquitination
GO:0032717 IDA negative regulation of interleukin-8 production
GO:0035871 IDA protein K11-linked deubiquitination
GO:0043124 IDA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0070530 IEA K63-linked polyubiquitin binding
GO:0070536 IDA protein K63-linked deubiquitination
GO:0071108 ISS protein K48-linked deubiquitination
GO:1900181 IDA negative regulation of protein localization to nucleus
GO:1990380 IDA Lys48-specific deubiquitinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017220 otud7b protein_coding Danio_rerio
ENSMUSG00000038495 Otud7b protein_coding Mus_musculus

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