ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: OTU deubiquitinase 7B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000581312 OTUD7B-001 ENSG00000264522 9606 - 1:149937812-150010676 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000581312
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000581312 0.178±0.00 2.018±0.84 1.821±0.00 1.598±0.80

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0002385 ISS mucosal immune response
GO:0003677 IEA DNA binding
GO:0004221 ISS ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006508 IEA proteolysis
GO:0008234 ISS cysteine-type peptidase activity
GO:0008270 IEA zinc ion binding
GO:0016579 IEA protein deubiquitination
GO:0032717 IDA negative regulation of interleukin-8 production
GO:0035871 IDA protein K11-linked deubiquitination
GO:0043124 IDA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0070530 IEA K63-linked polyubiquitin binding
GO:0070536 IDA protein K63-linked deubiquitination
GO:0071108 ISS protein K48-linked deubiquitination
GO:1900181 IDA negative regulation of protein localization to nucleus
GO:1990380 IDA Lys48-specific deubiquitinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000035519 Otud7b-201 protein_coding Mus_musculus 0 3478
ENSMUST00000098849 Otud7b-002 protein_coding Mus_musculus 0 3271
ENSMUST00000090785 Otud7b-001 protein_coding Mus_musculus 0 3271
ENSMUST00000138206 Otud7b-003 protein_coding Mus_musculus 0 1053
ENSMUST00000177534 Otud7a-002 protein_coding Mus_musculus 0 590
ENSMUST00000135263 Otud7b-006 processed_transcript Mus_musculus 0 549
ENSMUST00000058476 Otud7a-001 protein_coding Mus_musculus 0 484
ENSMUST00000132980 Otud7b-004 protein_coding Mus_musculus 0 414
ENSMUST00000146660 Otud7b-005 processed_transcript Mus_musculus 0 396
ENSMUST00000105503 Armc2-006 retained_intron Mus_musculus 0.0006 53

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