ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000142 Axin2 10090 + 11:108920349-108950783 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000052915 Axin2-001 108920349-108950783 protein_coding
  ENSMUST00000106711 Axin2-002 108923181-108949511 protein_coding
  ENSMUST00000139682 Axin2-003 108943621-108950783 processed_transcript
  ENSMUST00000140821 Axin2-005 108920800-108923583 protein_coding
  ENSMUST00000144130 Axin2-007 108938874-108942559 processed_transcript
  ENSMUST00000144511 Axin2-004 108921648-108923494 protein_coding
  ENSMUST00000152909 Axin2-006 108921336-108923598 protein_coding

Mus musculus Ensembl GRCm38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000052915ENSMUST00000106711ENSMUST00000139682
Transcript ID C166 Tie2+ EC mES
ENSMUST00000052915 0.101±0.03 4.290±0.88 6.091±1.59
ENSMUST00000106711 0.058±0.02 N/A 2.284±0.00
ENSMUST00000139682 0.063±0.01 1.488±0.00 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001756 IDA somitogenesis
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0001957 IMP intramembranous ossification
GO:0003139 IGI secondary heart field specification
GO:0003413 IMP chondrocyte differentiation involved in endochondral bone morphogenesis
GO:0005096 IBA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005813 IDA centrosome
GO:0005881 IBA cytoplasmic microtubule
GO:0005886 IBA plasma membrane
GO:0005938 IBA cell cortex
GO:0006355 IBA regulation of transcription, DNA-templated
GO:0008013 IBA beta-catenin binding
GO:0008219 IBA cell death
GO:0008283 IMP cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0009950 IBA dorsal/ventral axis specification
GO:0010718 IEA positive regulation of epithelial to mesenchymal transition
GO:0010942 IEA positive regulation of cell death
GO:0014069 IBA postsynaptic density
GO:0016023 IBA cytoplasmic membrane-bounded vesicle
GO:0019899 IEA enzyme binding
GO:0019901 IBA protein kinase binding
GO:0030111 IDA regulation of Wnt signaling pathway
GO:0030282 IMP bone mineralization
GO:0030877 IBA beta-catenin destruction complex
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032423 IEA regulation of mismatch repair
GO:0034613 IEA cellular protein localization
GO:0035412 IBA regulation of catenin import into nucleus
GO:0035414 IEA negative regulation of catenin import into nucleus
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0042476 IEA odontogenesis
GO:0043547 IBA positive regulation of GTPase activity
GO:0043570 IEA maintenance of DNA repeat elements
GO:0045668 IMP negative regulation of osteoblast differentiation
GO:0048255 IEA mRNA stabilization
GO:0061181 IMP regulation of chondrocyte development
GO:0070016 IBA armadillo repeat domain binding
GO:0070411 IPI I-SMAD binding
GO:0070602 IMP regulation of centromeric sister chromatid cohesion
GO:0071407 IBA cellular response to organic cyclic compound
GO:0090090 IBA negative regulation of canonical Wnt signaling pathway
GO:0090244 IBA Wnt signaling pathway involved in somitogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000168646 AXIN2 axin 2 protein_coding Homo_sapiens

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