ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000002111 Spi1 10090 + 2:91082390-91115756 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000002180 Spi1-001 91096096-91115756 protein_coding
  ENSMUST00000131400 Spi1-004 91082408-91090310 processed_transcript
  ENSMUST00000132741 Spi1-002 91096780-91113315 protein_coding
  ENSMUST00000169852 Spi1-003 91082390-91114366 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000002180ENSMUST00000131400ENSMUST00000169852
Transcript ID C166 Tie2+ EC mES
ENSMUST00000002180 0.015±0.00 0.056±0.04 0.110±0.09
ENSMUST00000131400 N/A N/A 0.065±0.00
ENSMUST00000169852 N/A 0.583±0.00 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001047 IEA core promoter binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001205 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001944 IMP vasculature development
GO:0002320 IMP lymphoid progenitor cell differentiation
GO:0002573 IMP myeloid leukocyte differentiation
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IC transcription factor complex
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0030098 IDA lymphocyte differentiation
GO:0030218 IMP erythrocyte differentiation
GO:0030225 IDA macrophage differentiation
GO:0030851 IDA granulocyte differentiation
GO:0035019 IDA somatic stem cell maintenance
GO:0043011 IMP myeloid dendritic cell differentiation
GO:0043565 IDA sequence-specific DNA binding
GO:0043966 IEA histone H3 acetylation
GO:0044027 IEA hypermethylation of CpG island
GO:0045347 IDA negative regulation of MHC class II biosynthetic process
GO:0045646 IEA regulation of erythrocyte differentiation
GO:0045814 IEA negative regulation of gene expression, epigenetic
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051525 IPI NFAT protein binding
GO:0060033 IMP anatomical structure regression
GO:0090241 IEA negative regulation of histone H4 acetylation
GO:1902262 IMP apoptotic process involved in patterning of blood vessels

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000767 spi1b protein_coding Danio_rerio
ENSDARG00000067797 spi1a protein_coding Danio_rerio
ENSG00000066336 SPI1 Spi-1 proto-oncogene protein_coding Homo_sapiens

Loading