ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005102 Eif2ak4 10090 + 2:118388618-118475234 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005233 Eif2ak4-001 118388618-118475234 protein_coding
  ENSMUST00000102527 Eif2ak4-201 118389112-118475231 protein_coding
  ENSMUST00000110869 Eif2ak4-006 118438842-118452290 protein_coding
  ENSMUST00000110870 Eif2ak4-004 118412346-118475234 protein_coding
  ENSMUST00000110872 Eif2ak4-003 118389112-118475232 protein_coding
  ENSMUST00000110874 Eif2ak4-002 118388847-118475234 protein_coding
  ENSMUST00000110877 Eif2ak4-005 118388618-118428213 protein_coding
  ENSMUST00000125281 Eif2ak4-007 118457160-118462094 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000005233ENSMUST00000102527ENSMUST00000110870ENSMUST00000110872ENSMUST00000110874
Transcript ID C166 Tie2+ EC mES
ENSMUST00000005233 7.642±2.54 6.091±0.36 3.940±0.67
ENSMUST00000102527 1.370±0.01 N/A N/A
ENSMUST00000110870 N/A 1.425±0.09 N/A
ENSMUST00000110872 1.315±0.00 N/A N/A
ENSMUST00000110874 N/A 0.980±0.31 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008W0 CIL_0008W0_0002 VISTA
CIL_0006QT CIL_0006QT_0002 CGP
CIL_0006QZ CIL_0006QZ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004694 IDA eukaryotic translation initiation factor 2alpha kinase activity
GO:0005524 IEA ATP binding
GO:0006446 ISS regulation of translational initiation
GO:0006468 IEA protein phosphorylation
GO:0009267 IDA cellular response to starvation
GO:0017148 IGI negative regulation of translation
GO:0022626 ISS cytosolic ribosome
GO:0030968 IMP endoplasmic reticulum unfolded protein response
GO:0042803 IEA protein homodimerization activity
GO:0043558 IDA regulation of translational initiation in response to stress

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000128829 EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 protein_coding Homo_sapiens

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