ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000009569 Mkl2 10090 + 16:13256481-13417529 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000009713 Mkl2-003 13256481-13415063 protein_coding
  ENSMUST00000056715 Mkl2-201 13265076-13332919 protein_coding
  ENSMUST00000115809 Mkl2-004 13256506-13332922 protein_coding
  ENSMUST00000149359 Mkl2-001 13358421-13417529 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECENSMUST00000009713ENSMUST00000149359
Transcript ID C166 Tie2+ EC
ENSMUST00000009713 N/A 3.798±1.73
ENSMUST00000149359 1.088±0.30 4.430±3.03

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002RP CIL_0002RP_0003 CGP
CIL_0007DW CIL_0007DW_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001889 IMP liver development
GO:0003007 IMP heart morphogenesis
GO:0003676 IEA nucleic acid binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003713 IEA transcription coactivator activity
GO:0003779 IDA actin binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0007507 IMP heart development
GO:0010467 IMP gene expression
GO:0010468 IMP regulation of gene expression
GO:0045844 IEA positive regulation of striated muscle tissue development
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048514 IMP blood vessel morphogenesis
GO:0048568 IMP embryonic organ development
GO:0048738 IMP cardiac muscle tissue development
GO:0051145 IMP smooth muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076867 mkl2b protein_coding Danio_rerio
ENSDARG00000088307 mkl2a protein_coding Danio_rerio
ENSG00000186260 MKL2 MKL/myocardin-like 2 protein_coding Homo_sapiens

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