ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000016933 Plcg1 10090 + 2:160731300-160775760 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017077 Plcg1-008 160740987-160762506 processed_transcript
  ENSMUST00000103115 Plcg1-001 160731310-160775760 protein_coding
  ENSMUST00000109462 Plcg1-003 160731733-160763286 protein_coding
  ENSMUST00000124652 Plcg1-007 160754572-160759447 processed_transcript
  ENSMUST00000129568 Plcg1-005 160754547-160755169 retained_intron
  ENSMUST00000143997 Plcg1-002 160760118-160762217 protein_coding
  ENSMUST00000147254 Plcg1-006 160754906-160757147 retained_intron
  ENSMUST00000151590 Plcg1-004 160731300-160762502 nonsense_mediated_decay
  ENSMUST00000173061 Plcg1-012 160754067-160754864 retained_intron
  ENSMUST00000173335 Plcg1-010 160752552-160758907 retained_intron
  ENSMUST00000173791 Plcg1-009 160752487-160762155 retained_intron
  ENSMUST00000174885 Plcg1-011 160731699-160747888 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000109462
Transcript ID C166 Tie2+ EC mES
ENSMUST00000109462 33.900±2.57 29.405±10.38 26.802±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008TO CIL_0008TO_0002 VISTA
CIL_0009AU CIL_0009AU_0002 VISTA
CIL_0007XA CIL_0007XA_0002 VISTA
CIL_0008MI CIL_0008MI_0002 VISTA
CIL_0008QO CIL_0008QO_0002 VISTA
CIL_0009AV CIL_0009AV_0002 VISTA
CIL_0004EC CIL_0004EC_0002 CGP
CIL_0002I4 CIL_0002I4_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001726 ISS ruffle
GO:0004435 IEA phosphatidylinositol phospholipase C activity
GO:0004871 IEA signal transducer activity
GO:0005168 IEA neurotrophin TRKA receptor binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005737 ISO cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0007173 IEA epidermal growth factor receptor signaling pathway
GO:0008152 IEA metabolic process
GO:0008180 IEA COP9 signalosome
GO:0009395 IEA phospholipid catabolic process
GO:0010634 ISS positive regulation of epithelial cell migration
GO:0016042 IEA lipid catabolic process
GO:0016477 IEA cell migration
GO:0019722 IEA calcium-mediated signaling
GO:0019901 IEA protein kinase binding
GO:0030027 ISS lamellipodium
GO:0030971 IPI receptor tyrosine kinase binding
GO:0035254 IPI glutamate receptor binding
GO:0035556 IEA intracellular signal transduction
GO:0042995 IEA cell projection
GO:0043536 IEA positive regulation of blood vessel endothelial cell migration
GO:0045766 IEA positive regulation of angiogenesis
GO:0050852 IDA T cell receptor signaling pathway
GO:0051281 IEA positive regulation of release of sequestered calcium ion into cytosol
GO:0071364 ISS cellular response to epidermal growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000124181 PLCG1 phospholipase C, gamma 1 protein_coding Homo_sapiens

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