ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018012 Rac3 10090 + 11:120721470-120723969 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018156 Rac3-001 120721470-120723969 protein_coding
  ENSMUST00000134322 Rac3-003 120722014-120723565 processed_transcript
  ENSMUST00000142229 Rac3-002 120721573-120723606 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000018156ENSMUST00000134322ENSMUST00000142229
Transcript ID C166 Tie2+ EC mES
ENSMUST00000018156 0.511±0.24 1.681±1.38 2.700±0.82
ENSMUST00000134322 0.275±0.08 N/A N/A
ENSMUST00000142229 0.418±0.19 0.205±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004VQ CIL_0004VQ_0002 CGP
CIL_00043Y CIL_00043Y_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 ISS GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005886 IEA plasma membrane
GO:0007264 IEA small GTPase mediated signal transduction
GO:0012505 ISS endomembrane system
GO:0030031 ISS cell projection assembly
GO:0030036 ISS actin cytoskeleton organization
GO:0030426 ISO growth cone
GO:0031175 IDA neuron projection development
GO:0031941 ISO filamentous actin
GO:0033630 ISS positive regulation of cell adhesion mediated by integrin
GO:0043005 ISO neuron projection
GO:0043025 ISO neuronal cell body
GO:0048306 IEA calcium-dependent protein binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0050885 IMP neuromuscular process controlling balance
GO:0050905 IMP neuromuscular process
GO:0070062 IEA extracellular vesicular exosome
GO:0071944 ISS cell periphery
GO:1900026 ISS positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020795 rac3b protein_coding Danio_rerio
ENSDARG00000090062 rac3a protein_coding Danio_rerio
ENSG00000169750 RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) protein_coding Homo_sapiens

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