ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169750 RAC3 9606 + 17:82031624-82034204 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306897 RAC3-001 82031624-82034202 protein_coding
  ENST00000580965 RAC3-002 82032061-82033790 protein_coding
  ENST00000584341 RAC3-003 82032184-82033772 protein_coding
  ENST00000585014 RAC3-004 82032878-82034204 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000306897ENST00000580965ENST00000584341ENST00000585014
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000306897 23.315±4.25 9.261±4.23 N/A 4.355±0.00 13.277±14.04
ENST00000580965 9.828±2.80 2.726±1.30 1.806±0.00 5.513±0.00 4.660±3.94
ENST00000584341 N/A 2.639±0.00 N/A N/A 1.028±0.97
ENST00000585014 20.823±0.00 N/A 0.811±0.00 5.365±0.00 2.186±0.89

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004VQ CIL_0004VQ_0001 CGP
CIL_00043Y CIL_00043Y_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IDA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006184 IDA:IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007264 IEA:TAS small GTPase mediated signal transduction
GO:0012505 IDA endomembrane system
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0030031 IDA cell projection assembly
GO:0030036 IDA actin cytoskeleton organization
GO:0030426 IDA growth cone
GO:0031175 IEA neuron projection development
GO:0031941 IDA filamentous actin
GO:0033630 IDA positive regulation of cell adhesion mediated by integrin
GO:0035556 TAS intracellular signal transduction
GO:0043005 IDA neuron projection
GO:0043025 IDA neuronal cell body
GO:0048306 IPI calcium-dependent protein binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050885 IEA neuromuscular process controlling balance
GO:0050905 IEA neuromuscular process
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070062 IDA extracellular vesicular exosome
GO:0071944 IDA cell periphery
GO:1900026 IDA positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020795 rac3b protein_coding Danio_rerio
ENSDARG00000090062 rac3a protein_coding Danio_rerio
ENSMUSG00000018012 Rac3 protein_coding Mus_musculus

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