ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018209 Stk4 10090 + 2:164070322-164155524 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018353 Stk4-001 164074138-164155524 protein_coding
  ENSMUST00000088291 Stk4-003 164110201-164155524 protein_coding
  ENSMUST00000134078 Stk4-004 164070322-164086591 protein_coding
  ENSMUST00000137866 Stk4-002 164099720-164118369 protein_coding
  ENSMUST00000153319 Stk4-005 164081597-164096857 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000018353ENSMUST00000088291
Transcript ID C166 Tie2+ EC mES
ENSMUST00000018353 20.838±2.57 4.209±0.55 3.478±1.36
ENSMUST00000088291 N/A 0.989±0.13 2.088±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002ZU CIL_0002ZU_0002 CGP
CIL_0003UT CIL_0003UT_0002 CGP
CIL_0003US CIL_0003US_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0000902 ISO cell morphogenesis
GO:0001569 IGI patterning of blood vessels
GO:0001841 IGI neural tube formation
GO:0003157 IGI endocardium development
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006468 ISS protein phosphorylation
GO:0006915 ISS apoptotic process
GO:0007417 IGI central nervous system development
GO:0008134 IEA transcription factor binding
GO:0008285 IGI negative regulation of cell proliferation
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0030216 IGI keratinocyte differentiation
GO:0035329 IGI hippo signaling
GO:0035556 IEA intracellular signal transduction
GO:0042802 IEA identical protein binding
GO:0042803 ISO protein homodimerization activity
GO:0043065 IGI positive regulation of apoptotic process
GO:0046621 IGI negative regulation of organ growth
GO:0046777 ISO protein autophosphorylation
GO:0046983 IEA protein dimerization activity
GO:0060215 IGI primitive hemopoiesis
GO:0060706 IGI cell differentiation involved in embryonic placenta development
GO:0090090 IGI negative regulation of canonical Wnt signaling pathway
GO:0097284 IGI hepatocyte apoptotic process
GO:1902043 IGI positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000101109 STK4 serine/threonine kinase 4 protein_coding Homo_sapiens

Loading