| Transcript ID | C166 | Tie2+ EC | mES |
|---|---|---|---|
| ENSMUST00000108920 | 22.543±3.31 | 20.507±1.46 | 0.581±0.35 |
ANGIOGENES: A knowledge database for angiogenesis
Institute of Cardiovascular Regeneration, Goethe University Frankfurt
Gene Info | |||||
|---|---|---|---|---|---|
| Description: | |||||
| Gene Accession | Gene Name | Tax ID | Strand | Position | Gene Biotype |
ENSMUSG00000018899  |
Irf1 | 10090 | + |
11:53770014-53778374  |
protein_coding |
| Transcript Accession | Transcript Name | Position | Transcript Biotype | ||
| ENSMUST00000019043 |
Irf1-002 | 53770495-53777323 | protein_coding | ||
| ENSMUST00000108920 |
Irf1-001 | 53770014-53777323 | protein_coding | ||
| ENSMUST00000108922 |
Irf1-008 | 53770051-53778374 | protein_coding | ||
| ENSMUST00000123376 |
Irf1-005 | 53770487-53774194 | protein_coding | ||
| ENSMUST00000128336 |
Irf1-004 | 53770071-53776378 | processed_transcript | ||
| ENSMUST00000133291 |
Irf1-006 | 53770509-53773957 | protein_coding | ||
| ENSMUST00000138913 |
Irf1-007 | 53770477-53772938 | protein_coding | ||
| ENSMUST00000140866 |
Irf1-010 | 53770048-53775103 | protein_coding | ||
| ENSMUST00000142221 |
Irf1-009 | 53770105-53774085 | nonsense_mediated_decay | ||
| ENSMUST00000153054 |
Irf1-003 | 53773153-53774130 | retained_intron | ||
Expression Patterns
|
Conserved Regions | ||
|---|---|---|
| Region ID | Sub-Region | Region Type |
| CIL_0007RF | CIL_0007RF_0002 | VISTA |
| CIL_00093D | CIL_00093D_0002 | VISTA |
Gene Ontology |
||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0000790 | IEA | nuclear chromatin |
| GO:0000975 | IEA | regulatory region DNA binding |
| GO:0000978 | IEA | RNA polymerase II core promoter proximal region sequence-specific DNA binding |
| GO:0002819 | TAS | regulation of adaptive immune response |
| GO:0003677 | IDA | DNA binding |
| GO:0003700 | IDA | sequence-specific DNA binding transcription factor activity |
| GO:0005515 | IPI | protein binding |
| GO:0005634 | IC | nucleus |
| GO:0005737 | IDA | cytoplasm |
| GO:0006351 | IEA | transcription, DNA-templated |
| GO:0006915 | ISS | apoptotic process |
| GO:0007050 | ISS | cell cycle arrest |
| GO:0010468 | IMP | regulation of gene expression |
| GO:0032481 | IMP | positive regulation of type I interferon production |
| GO:0032728 | ISS | positive regulation of interferon-beta production |
| GO:0032825 | TAS | positive regulation of natural killer cell differentiation |
| GO:0034124 | IMP | regulation of MyD88-dependent toll-like receptor signaling pathway |
| GO:0035458 | IEA | cellular response to interferon-beta |
| GO:0043374 | IMP | CD8-positive, alpha-beta T cell differentiation |
| GO:0043565 | IDA | sequence-specific DNA binding |
| GO:0045084 | IDA | positive regulation of interleukin-12 biosynthetic process |
| GO:0045088 | TAS | regulation of innate immune response |
| GO:0045590 | IMP | negative regulation of regulatory T cell differentiation |
| GO:0045627 | TAS | positive regulation of T-helper 1 cell differentiation |
| GO:0045629 | TAS | negative regulation of T-helper 2 cell differentiation |
| GO:0045892 | IDA | negative regulation of transcription, DNA-templated |
| GO:0045893 | IDA | positive regulation of transcription, DNA-templated |
| GO:0045944 | IDA | positive regulation of transcription from RNA polymerase II promoter |
| GO:0051607 | ISS | defense response to virus |
| GO:0060333 | IMP | interferon-gamma-mediated signaling pathway |
| GO:0071260 | IEA | cellular response to mechanical stimulus |
| GO:2000564 | IMP | regulation of CD8-positive, alpha-beta T cell proliferation |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Description | Biotype | Species | |
|
ENSG00000125347
|
IRF1 | interferon regulatory factor 1 | protein_coding | Homo_sapiens | |
