ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019577 Pdk4 10090 - 6:5483351-5496309 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000019721 Pdk4-001 5483351-5496309 protein_coding
  ENSMUST00000134068 Pdk4-002 5494863-5496275 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000019721ENSMUST00000134068
Transcript ID C166 Tie2+ EC mES
ENSMUST00000019721 1.735±0.34 7.370±7.28 0.232±0.13
ENSMUST00000134068 N/A 0.689±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008H4 CIL_0008H4_0002 VISTA
CIL_0006QC CIL_0006QC_0003 CGP
CIL_00053G CIL_00053G_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 TAS protein serine/threonine/tyrosine kinase activity
GO:0004740 ISS pyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0006006 IEA glucose metabolic process
GO:0006086 TAS acetyl-CoA biosynthetic process from pyruvate
GO:0006468 IEA protein phosphorylation
GO:0006885 IMP regulation of pH
GO:0008286 IMP insulin receptor signaling pathway
GO:0009267 ISS cellular response to starvation
GO:0010510 IMP regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0010565 IMP regulation of cellular ketone metabolic process
GO:0010906 IMP regulation of glucose metabolic process
GO:0042304 IMP regulation of fatty acid biosynthetic process
GO:0042593 IMP glucose homeostasis
GO:0042594 IMP response to starvation
GO:0045124 IMP regulation of bone resorption
GO:0046320 IMP regulation of fatty acid oxidation
GO:0071398 ISS cellular response to fatty acid
GO:0072593 ISS reactive oxygen species metabolic process
GO:2000811 IEA negative regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054848 pdk4 protein_coding Danio_rerio
ENSG00000004799 PDK4 pyruvate dehydrogenase kinase, isozyme 4 protein_coding Homo_sapiens

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