ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019979 Apaf1 10090 - 10:90989311-91082770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020157 Apaf1-001 90989318-91082770 protein_coding
  ENSMUST00000159110 Apaf1-002 90989311-91082662 protein_coding
  ENSMUST00000159457 Apaf1-006 90995733-91000411 processed_transcript
  ENSMUST00000160725 Apaf1-008 90989313-90991590 retained_intron
  ENSMUST00000160788 Apaf1-004 91066890-91082770 protein_coding
  ENSMUST00000161095 Apaf1-007 90996740-90999719 retained_intron
  ENSMUST00000161987 Apaf1-005 91065392-91082429 protein_coding
  ENSMUST00000162618 Apaf1-003 90990602-91082704 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000020157ENSMUST00000159110ENSMUST00000160725ENSMUST00000161987ENSMUST00000162618
Transcript ID C166 Tie2+ EC mES
ENSMUST00000020157 1.105±0.34 1.915±1.14 2.181±0.35
ENSMUST00000159110 5.417±1.43 1.052±0.28 4.202±1.93
ENSMUST00000160725 N/A N/A 47.184±22.03
ENSMUST00000161987 N/A 2.233±0.00 N/A
ENSMUST00000162618 1.061±0.00 3.080±0.72 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00090D CIL_00090D_0002 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001843 IMP neural tube closure
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005829 IDA cytosol
GO:0006919 IGI activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007275 IMP multicellular organismal development
GO:0007420 IMP brain development
GO:0008635 IBA activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0008656 IPI cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0030900 IMP forebrain development
GO:0042802 IPI identical protein binding
GO:0043293 IBA apoptosome
GO:0043531 IEA ADP binding
GO:0051402 IGI neuron apoptotic process
GO:0070062 IEA extracellular vesicular exosome
GO:1902510 IGI regulation of apoptotic DNA fragmentation
GO:2001235 IGI positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021239 apaf1 protein_coding Danio_rerio
ENSG00000120868 APAF1 apoptotic peptidase activating factor 1 protein_coding Homo_sapiens

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