ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020395 Itk 10090 - 11:46325150-46389515 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020664 Itk-001 46325150-46389515 protein_coding
  ENSMUST00000101306 Itk-002 46344478-46389457 protein_coding
  ENSMUST00000109237 Itk-004 46325150-46389493 protein_coding
  ENSMUST00000155991 Itk-003 46363103-46389461 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; Tie2+ ECmESENSMUST00000020664ENSMUST00000109237
Transcript ID Tie2+ EC mES
ENSMUST00000020664 0.076±0.06 0.007±0.00
ENSMUST00000109237 0.017±0.01 0.007±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00094M CIL_00094M_0002 VISTA
CIL_00023X CIL_00023X_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001816 IMP cytokine production
GO:0001865 IGI NK T cell differentiation
GO:0002250 IMP adaptive immune response
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 ISS non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0005911 IDA cell-cell junction
GO:0007202 IMP activation of phospholipase C activity
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0032609 IGI interferon-gamma production
GO:0032633 IGI interleukin-4 production
GO:0035556 IEA intracellular signal transduction
GO:0046872 IEA metal ion binding
GO:0050852 IMP T cell receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017565 itk protein_coding Danio_rerio
ENSG00000113263 ITK IL2-inducible T-cell kinase protein_coding Homo_sapiens

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