ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020661 Dnmt3a 10090 + 12:3806007-3914443 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020991 Dnmt3a-001 3807030-3914443 protein_coding
  ENSMUST00000085826 Dnmt3a-003 3806498-3867484 retained_intron
  ENSMUST00000111186 Dnmt3a-201 3891744-3914443 protein_coding
  ENSMUST00000172509 Dnmt3a-008 3807058-3896995 protein_coding
  ENSMUST00000172689 Dnmt3a-005 3891728-3907842 protein_coding
  ENSMUST00000172719 Dnmt3a-017 3806527-3873381 protein_coding
  ENSMUST00000172749 Dnmt3a-013 3895593-3897365 protein_coding
  ENSMUST00000172816 Dnmt3a-007 3861021-3866162 protein_coding
  ENSMUST00000172879 Dnmt3a-011 3894824-3895676 protein_coding
  ENSMUST00000172913 Dnmt3a-016 3906816-3908547 protein_coding
  ENSMUST00000173197 Dnmt3a-009 3866191-3876062 protein_coding
  ENSMUST00000173700 Dnmt3a-002 3806007-3838814 retained_intron
  ENSMUST00000174102 Dnmt3a-010 3885449-3896121 protein_coding
  ENSMUST00000174272 Dnmt3a-014 3897420-3899685 retained_intron
  ENSMUST00000174483 Dnmt3a-004 3849635-3907887 nonsense_mediated_decay
  ENSMUST00000174733 Dnmt3a-015 3900281-3906792 nonsense_mediated_decay
  ENSMUST00000174774 Dnmt3a-012 3894869-3896976 protein_coding
  ENSMUST00000174817 Dnmt3a-006 3807160-3913491 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000020991ENSMUST00000111186ENSMUST00000172689ENSMUST00000174817
Transcript ID C166 Tie2+ EC mES
ENSMUST00000020991 8.852±0.85 1.111±0.08 2.094±0.60
ENSMUST00000111186 N/A 7.650±0.64 N/A
ENSMUST00000172689 N/A 8.228±0.00 17.660±6.81
ENSMUST00000174817 7.174±0.71 2.541±0.37 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000775 IDA chromosome, centromeric region
GO:0000791 ISS euchromatin
GO:0000792 IDA heterochromatin
GO:0001741 IDA XY body
GO:0003677 IDA:ISS DNA binding
GO:0003682 IDA chromatin binding
GO:0003886 IDA:ISS DNA (cytosine-5-)-methyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA:ISS nucleus
GO:0005720 IDA nuclear heterochromatin
GO:0005737 IDA:ISS cytoplasm
GO:0006306 IDA:ISS DNA methylation
GO:0006346 IDA methylation-dependent chromatin silencing
GO:0006349 IMP regulation of gene expression by genetic imprinting
GO:0006351 IEA transcription, DNA-templated
GO:0007283 IMP spermatogenesis
GO:0008168 TAS methyltransferase activity
GO:0010216 TAS maintenance of DNA methylation
GO:0010424 IEA DNA methylation on cytosine within a CG sequence
GO:0016363 ISS nuclear matrix
GO:0042802 IEA identical protein binding
GO:0043045 IMP DNA methylation involved in embryo development
GO:0043046 IMP DNA methylation involved in gamete generation
GO:0044027 IDA hypermethylation of CpG island
GO:0045322 IEA unmethylated CpG binding
GO:0046498 IEA S-adenosylhomocysteine metabolic process
GO:0046499 IEA S-adenosylmethioninamine metabolic process
GO:0046872 IEA metal ion binding
GO:0051718 IEA DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
GO:0071230 IDA cellular response to amino acid stimulus
GO:0090116 IDA:IEA C-5 methylation of cytosine

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005394 dnmt3aa protein_coding Danio_rerio
ENSDARG00000015566 dnmt3ab protein_coding Danio_rerio
ENSG00000119772 DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha protein_coding Homo_sapiens

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