ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020715 Ern1 10090 - 11:106394650-106487852 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001059 Ern1-001 106394650-106487796 protein_coding
  ENSMUST00000106799 Ern1-004 106458556-106487803 protein_coding
  ENSMUST00000106800 Ern1-005 106434681-106487808 protein_coding
  ENSMUST00000106801 Ern1-002 106413766-106487836 protein_coding
  ENSMUST00000131895 Ern1-003 106397451-106487852 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000001059ENSMUST00000106801
Transcript ID C166 Tie2+ EC mES
ENSMUST00000001059 7.178±1.60 2.223±0.88 0.349±0.00
ENSMUST00000106801 N/A 0.762±0.00 0.740±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0009B9 CIL_0009B9_0002 VISTA
CIL_0006GW CIL_0006GW_0002 CGP
CIL_0004WB CIL_0004WB_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0004519 IDA endonuclease activity
GO:0004521 IDA endoribonuclease activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0005637 IDA nuclear inner membrane
GO:0005739 IDA mitochondrion
GO:0005789 IDA endoplasmic reticulum membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 ISS protein phosphorylation
GO:0006987 ISS activation of signaling protein activity involved in unfolded protein response
GO:0007050 IDA cell cycle arrest
GO:0019899 IEA enzyme binding
GO:0030176 IEA integral component of endoplasmic reticulum membrane
GO:0030968 IDA endoplasmic reticulum unfolded protein response
GO:0042802 IEA identical protein binding
GO:0046777 IDA protein autophosphorylation
GO:0070055 IEA HAC1-type intron splice site recognition and cleavage
GO:0070059 IDA intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0090305 IDA nucleic acid phosphodiester bond hydrolysis
GO:0090502 IDA RNA phosphodiester bond hydrolysis, endonucleolytic
GO:1900103 IEA positive regulation of endoplasmic reticulum unfolded protein response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013997 ern1 protein_coding Danio_rerio
ENSG00000178607 ERN1 endoplasmic reticulum to nucleus signaling 1 protein_coding Homo_sapiens

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