ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022788 Fgd4 10090 - 16:16416917-16600549 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000069284 Fgd4-006 16422602-16527411 protein_coding
  ENSMUST00000159058 Fgd4-005 16472266-16559990 retained_intron
  ENSMUST00000159542 Fgd4-010 16462014-16600549 protein_coding
  ENSMUST00000161188 Fgd4-201 16435706-16504222 protein_coding
  ENSMUST00000161624 Fgd4-009 16487115-16600345 retained_intron
  ENSMUST00000161861 Fgd4-001 16416917-16560219 protein_coding
  ENSMUST00000162045 Fgd4-003 16452719-16560211 retained_intron
  ENSMUST00000162124 Fgd4-004 16453480-16560211 retained_intron
  ENSMUST00000162414 Fgd4-007 16482492-16600039 retained_intron
  ENSMUST00000162542 Fgd4-011 16483471-16527411 retained_intron
  ENSMUST00000162671 Fgd4-008 16422563-16599978 protein_coding
  ENSMUST00000172181 Fgd4-002 16435706-16560046 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000159058ENSMUST00000161624ENSMUST00000162045ENSMUST00000162671
Transcript ID C166 Tie2+ EC mES
ENSMUST00000159058 N/A 0.333±0.00 N/A
ENSMUST00000161624 0.192±0.08 0.546±0.20 0.617±0.02
ENSMUST00000162045 0.065±0.00 1.148±0.29 0.539±0.06
ENSMUST00000162671 N/A 0.097±0.00 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 ISO actin binding
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IEA cytoplasm
GO:0007257 ISO activation of JUN kinase activity
GO:0015629 IEA actin cytoskeleton
GO:0030027 IDA lamellipodium
GO:0030032 IDA lamellipodium assembly
GO:0030035 IDA microspike assembly
GO:0030175 IDA filopodium
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060248 FGD4 (1 of 2) protein_coding Danio_rerio
ENSG00000139132 FGD4 FYVE, RhoGEF and PH domain containing 4 protein_coding Homo_sapiens

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