ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022957 Itsn1 10090 + 16:91729281-91920597 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000056482 Itsn1-003 91729371-91871655 protein_coding
  ENSMUST00000064797 Itsn1-008 91729353-91913988 protein_coding
  ENSMUST00000095909 Itsn1-002 91729370-91832353 protein_coding
  ENSMUST00000113993 Itsn1-005 91729592-91870497 protein_coding
  ENSMUST00000113996 Itsn1-010 91729373-91871653 protein_coding
  ENSMUST00000113999 Itsn1-006 91729353-91871651 protein_coding
  ENSMUST00000114001 Itsn1-004 91729281-91870210 protein_coding
  ENSMUST00000114002 Itsn1-001 91729353-91920597 protein_coding
  ENSMUST00000124094 Itsn1-022 91804622-91816917 processed_transcript
  ENSMUST00000125052 Itsn1-016 91887446-91909272 protein_coding
  ENSMUST00000126374 Itsn1-013 91853811-91863319 nonsense_mediated_decay
  ENSMUST00000131739 Itsn1-017 91899509-91909295 nonsense_mediated_decay
  ENSMUST00000131983 Itsn1-021 91729571-91793848 retained_intron
  ENSMUST00000133389 Itsn1-007 91784105-91828310 processed_transcript
  ENSMUST00000135057 Itsn1-009 91782161-91818629 protein_coding
  ENSMUST00000137575 Itsn1-019 91911959-91915160 processed_transcript
  ENSMUST00000138117 Itsn1-015 91862026-91871347 retained_intron
  ENSMUST00000139890 Itsn1-020 91729466-91782378 retained_intron
  ENSMUST00000141073 Itsn1-028 91877553-91893939 processed_transcript
  ENSMUST00000141625 Itsn1-018 91899511-91909272 protein_coding
  ENSMUST00000143023 Itsn1-027 91842628-91853260 protein_coding
  ENSMUST00000144101 Itsn1-025 91827537-91828273 retained_intron
  ENSMUST00000151044 Itsn1-024 91816826-91827897 processed_transcript
  ENSMUST00000153741 Itsn1-011 91839788-91853260 nonsense_mediated_decay
  ENSMUST00000154967 Itsn1-026 91839699-91851316 retained_intron
  ENSMUST00000156841 Itsn1-023 91804636-91812291 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000056482ENSMUST00000095909ENSMUST00000113996ENSMUST00000113999ENSMUST00000114002
Transcript ID C166 Tie2+ EC mES
ENSMUST00000056482 28.618±1.75 3.658±1.95 6.135±2.40
ENSMUST00000095909 N/A 0.985±0.52 1.026±0.30
ENSMUST00000113996 N/A 0.949±0.36 2.414±0.00
ENSMUST00000113999 N/A 1.316±0.00 N/A
ENSMUST00000114002 N/A 0.104±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00078C CIL_00078C_0002 CGP
CIL_0005TE CIL_0005TE_0002 CGP
CIL_00078A CIL_00078A_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005886 IEA plasma membrane
GO:0005905 IEA coated pit
GO:0006897 IEA endocytosis
GO:0007264 IDA small GTPase mediated signal transduction
GO:0019209 IDA kinase activator activity
GO:0030027 IDA lamellipodium
GO:0030054 IEA cell junction
GO:0030139 IDA endocytic vesicle
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032947 IEA protein complex scaffold
GO:0042327 IDA positive regulation of phosphorylation
GO:0043005 IEA neuron projection
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045202 IEA synapse
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0070064 IEA proline-rich region binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000086 itsn1 protein_coding Danio_rerio
ENSG00000205726 ITSN1 intersectin 1 (SH3 domain protein) protein_coding Homo_sapiens

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