ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023034 Nr4a1 10090 + 15:101266846-101274792 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023779 Nr4a1-201 101266846-101274792 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000023779
Transcript ID C166 Tie2+ EC mES
ENSMUST00000023779 11.397±2.26 110.594±103.16 7.103±2.88

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006K0 CIL_0006K0_0002 CGP
CIL_0006JQ CIL_0006JQ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0002042 IEA cell migration involved in sprouting angiogenesis
GO:0003677 IDA DNA binding
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006915 IMP apoptotic process
GO:0008270 IEA zinc ion binding
GO:0010035 ISA response to inorganic substance
GO:0030522 IEA intracellular receptor signaling pathway
GO:0035767 IEA endothelial cell chemotaxis
GO:0035914 IMP skeletal muscle cell differentiation
GO:0035924 IEA cellular response to vascular endothelial growth factor stimulus
GO:0042803 IDA protein homodimerization activity
GO:0043065 IDA positive regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IDA sequence-specific DNA binding
GO:0044344 IEA cellular response to fibroblast growth factor stimulus
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0071310 IDA cellular response to organic substance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000796 nr4a1 protein_coding Danio_rerio
ENSG00000123358 NR4A1 nuclear receptor subfamily 4, group A, member 1 protein_coding Homo_sapiens

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