ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024134 Six2 10090 - 17:85684277-85688274 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024947 Six2-201 85684282-85688254 protein_coding
  ENSMUST00000163568 Six2-001 85684277-85688274 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000024947ENSMUST00000163568
Transcript ID C166 Tie2+ EC mES
ENSMUST00000024947 0.023±0.00 0.324±0.25 1.970±0.56
ENSMUST00000163568 0.019±0.00 0.170±0.04 1.398±1.01

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007KD CIL_0007KD_0002 UCNEbase
CIL_00083B CIL_00083B_0002 VISTA
CIL_0009CD CIL_0009CD_0002 VISTA
CIL_0009CC CIL_0009CC_0002 VISTA
CIL_0007WX CIL_0007WX_0002 VISTA
CIL_0001NN CIL_0001NN_0002 CGP
CIL_0000RS CIL_0000RS_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001656 IMP metanephros development
GO:0001822 ISS kidney development
GO:0002062 IMP chondrocyte differentiation
GO:0003337 IEP mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006606 IDA protein import into nucleus
GO:0007501 IDA mesodermal cell fate specification
GO:0008134 IPI transcription factor binding
GO:0008283 ISS cell proliferation
GO:0009948 IDA anterior/posterior axis specification
GO:0016477 ISS cell migration
GO:0030278 IMP regulation of ossification
GO:0032330 IMP regulation of chondrocyte differentiation
GO:0032403 IDA protein complex binding
GO:0042474 IGI middle ear morphogenesis
GO:0043565 IDA sequence-specific DNA binding
GO:0045596 IMP negative regulation of cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048557 IMP embryonic digestive tract morphogenesis
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0048704 IGI embryonic skeletal system morphogenesis
GO:0072006 IMP nephron development
GO:0072028 IMP nephron morphogenesis
GO:0072038 IMP mesenchymal stem cell maintenance involved in nephron morphogenesis
GO:0072161 IMP mesenchymal cell differentiation involved in kidney development
GO:0090189 IMP regulation of branching involved in ureteric bud morphogenesis
GO:0097168 IMP mesenchymal stem cell proliferation
GO:1902732 IMP positive regulation of chondrocyte proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058004 six2a protein_coding Danio_rerio
ENSG00000170577 SIX2 SIX homeobox 2 protein_coding Homo_sapiens

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