ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024140 Epas1 10090 + 17:86753907-86833410 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024954 Epas1-201 86753907-86833410 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000024954
Transcript ID C166 Tie2+ EC mES
ENSMUST00000024954 4.368±3.37 106.557±41.69 11.618±5.06

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001NQ CIL_0001NQ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IMP angiogenesis
GO:0001666 ISO response to hypoxia
GO:0001892 IGI embryonic placenta development
GO:0001974 IMP blood vessel remodeling
GO:0002027 IMP regulation of heart rate
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006979 IMP response to oxidative stress
GO:0007005 IMP mitochondrion organization
GO:0007165 IEA signal transduction
GO:0007601 IMP visual perception
GO:0008134 IPI transcription factor binding
GO:0030097 IMP hemopoiesis
GO:0030154 IGI cell differentiation
GO:0030218 IMP erythrocyte differentiation
GO:0030324 IMP lung development
GO:0035035 ISS histone acetyltransferase binding
GO:0042415 IMP norepinephrine metabolic process
GO:0043129 IMP surfactant homeostasis
GO:0043565 IEA sequence-specific DNA binding
GO:0043619 IDA regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048469 IMP cell maturation
GO:0048625 IMP myoblast fate commitment
GO:0055072 IGI iron ion homeostasis
GO:0071456 ISS cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008697 epas1a protein_coding Danio_rerio
ENSDARG00000057671 epas1b protein_coding Danio_rerio
ENSG00000116016 EPAS1 endothelial PAS domain protein 1 protein_coding Homo_sapiens

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