ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000024954 Epas1-201 ENSMUSG00000024140 10090 + 17:86753907-86833410 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000024954
Transcript ID C166 Tie2+ EC mES
ENSMUST00000024954 4.368±3.37 106.557±41.69 11.618±5.06

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IMP angiogenesis
GO:0001666 ISO response to hypoxia
GO:0001892 IGI embryonic placenta development
GO:0001974 IMP blood vessel remodeling
GO:0002027 IMP regulation of heart rate
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006979 IMP response to oxidative stress
GO:0007005 IMP mitochondrion organization
GO:0007165 IEA signal transduction
GO:0007601 IMP visual perception
GO:0008134 IPI transcription factor binding
GO:0030097 IMP hemopoiesis
GO:0030154 IGI cell differentiation
GO:0030218 IMP erythrocyte differentiation
GO:0030324 IMP lung development
GO:0035035 ISS histone acetyltransferase binding
GO:0042415 IMP norepinephrine metabolic process
GO:0043129 IMP surfactant homeostasis
GO:0043565 IEA sequence-specific DNA binding
GO:0043619 IDA regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048469 IMP cell maturation
GO:0048625 IMP myoblast fate commitment
GO:0055072 IGI iron ion homeostasis
GO:0071456 ISS cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000244302 HIF3A-001 retained_intron Homo_sapiens 5e-19 100
ENST00000244303 HIF3A-007 protein_coding Homo_sapiens 9e-17 94
ENST00000263734 EPAS1-001 protein_coding Homo_sapiens 0 2972
ENST00000291300 HIF3A-009 retained_intron Homo_sapiens 5e-19 100
ENST00000300862 HIF3A-006 protein_coding Homo_sapiens 6e-19 100
ENST00000377670 HIF3A-003 protein_coding Homo_sapiens 1e-18 100
ENST00000449347 EPAS1-007 protein_coding Homo_sapiens 0 1086
ENST00000463191 EPAS1-005 retained_intron Homo_sapiens 0 734
ENST00000466465 EPAS1-010 retained_intron Homo_sapiens 0 981
ENST00000472815 HIF3A-004 protein_coding Homo_sapiens 7e-17 94
ENST00000475432 HIF3A-002 retained_intron Homo_sapiens 5e-19 100
ENST00000475822 EPAS1-003 processed_transcript Homo_sapiens 0 418
ENST00000483692 EPAS1-008 retained_intron Homo_sapiens 0 658
ENST00000525854 HIF3A-013 processed_transcript Homo_sapiens 3e-17 94
ENST00000528563 HIF3A-018 nonsense_mediated_decay Homo_sapiens 3e-19 100
ENST00000531043 HIF3A-016 nonsense_mediated_decay Homo_sapiens 0.00000000000004 82
ENST00000600383 HIF3A-023 protein_coding Homo_sapiens 8e-17 94

Loading