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                ),
                E_USER_WARNING
            );
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$value = array(
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)
$config = '_cake_core_'
$settings = array(
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	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

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                ),
                E_USER_WARNING
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$key = 'default_angiogenes_list'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
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	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

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                ),
                E_USER_WARNING
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$key = 'default_angiogenes_list'
$value = array(
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	(int) 6 => 'repeats',
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	(int) 8 => 'synonyms',
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$config = '_cake_model_'
$settings = array(
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	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
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	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

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                ),
                E_USER_WARNING
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$key = 'default_angiogenes_genes'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165

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                ),
                E_USER_WARNING
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$config = '_cake_model_'
$settings = array(
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	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
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$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 372
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

• HOME
• GENES
• TRANSCRIPTS
• HELP
• CONTACT

Gene Info
Description:
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000025932	Eya1	10090	-	1:14168954-14310235	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000027066		Eya1-201	14168954-14310200	protein_coding
	ENSMUST00000080664		Eya1-002	14169666-14310119	protein_coding
	ENSMUST00000168081		Eya1-001	14168958-14310235	protein_coding
	ENSMUST00000185329		Eya1-003	14301204-14310051	retained_intron
	ENSMUST00000185453		Eya1-006	14270707-14304628	protein_coding
	ENSMUST00000187790		Eya1-005	14270775-14309836	protein_coding
	ENSMUST00000188857		Eya1-007	14252600-14304619	protein_coding
	ENSMUST00000189526		Eya1-008	14207926-14231492	protein_coding
	ENSMUST00000190337		Eya1-004	14170643-14304570	protein_coding

Expression Patterns Split around values. Cell Line Name Tissue Condition Heat Map Numeric Values Transcript ID C166 Tie2+ EC mES ENSMUST00000027066 0.060±0.03 0.057±0.00 0.219±0.00 ENSMUST00000080664 0.037±0.02 0.053±0.00 N/A ENSMUST00000168081 N/A N/A 0.327±0.01 ENSMUST00000185329 N/A 0.029±0.00 0.128±0.00 ENSMUST00000187790 0.118±0.00 N/A N/A ENSMUST00000188857 0.080±0.00 N/A N/A ENSMUST00000190337 0.064±0.03 0.023±0.01 N/A

Conserved Regions
Region ID	Sub-Region	Region Type
CIL_00012M	CIL_00012M_0002	CGP
CIL_0007NF	CIL_0007NF_0002	UCNEbase
CIL_0003F4	CIL_0003F4_0002	CGP

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000132	IGI	establishment of mitotic spindle orientation
GO:0001656	IMP	metanephros development
GO:0001657	IGI	ureteric bud development
GO:0001658	IGI	branching involved in ureteric bud morphogenesis
GO:0003151	IMP	outflow tract morphogenesis
GO:0003723	IDA	RNA binding
GO:0004725	IDA	protein tyrosine phosphatase activity
GO:0005515	IPI	protein binding
GO:0005634	ISS	nucleus
GO:0005737	IDA	cytoplasm
GO:0006302	ISS	double-strand break repair
GO:0006351	IEA	transcription, DNA-templated
GO:0006470	IDA	protein dephosphorylation
GO:0007389	IGI	pattern specification process
GO:0007501	IDA	mesodermal cell fate specification
GO:0009887	IMP	organ morphogenesis
GO:0010212	ISS	response to ionizing radiation
GO:0014706	IGI	striated muscle tissue development
GO:0016576	ISS	histone dephosphorylation
GO:0016925	IDA	protein sumoylation
GO:0032993	IDA	protein-DNA complex
GO:0034613	IMP	cellular protein localization
GO:0035088	IMP	establishment or maintenance of apical/basal cell polarity
GO:0035335	IEA	peptidyl-tyrosine dephosphorylation
GO:0035909	IMP	aorta morphogenesis
GO:0042472	IMP	inner ear morphogenesis
GO:0042473	IMP	outer ear morphogenesis
GO:0042474	IMP	middle ear morphogenesis
GO:0043234	IDA	protein complex
GO:0045165	IMP	cell fate commitment
GO:0045664	IMP	regulation of neuron differentiation
GO:0045739	ISS	positive regulation of DNA repair
GO:0045747	IMP	positive regulation of Notch signaling pathway
GO:0045893	IDA	positive regulation of transcription, DNA-templated
GO:0045944	IGI	positive regulation of transcription from RNA polymerase II promoter
GO:0046872	IEA	metal ion binding
GO:0048665	IGI	neuron fate specification
GO:0048704	IMP	embryonic skeletal system morphogenesis
GO:0048752	IMP	semicircular canal morphogenesis
GO:0048856	IGI	anatomical structure development
GO:0050679	IMP	positive regulation of epithelial cell proliferation
GO:0060037	IMP	pharyngeal system development
GO:0060487	IGI	lung epithelial cell differentiation
GO:0071599	IGI	otic vesicle development
GO:0071600	IMP	otic vesicle morphogenesis
GO:0072513	IGI	positive regulation of secondary heart field cardioblast proliferation
GO:0090103	IMP	cochlea morphogenesis
GO:2001240	IMP	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000014259	eya1		protein_coding	Danio_rerio
ENSG00000104313	EYA1	EYA transcriptional coactivator and phosphatase 1	protein_coding	Homo_sapiens

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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

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                ),
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		'f1454297621ddcf07c418e47f67d3857' => '`Gene`.`gene_source`',
		'27d53785bfcd771f1901030b4bb87d02' => '`Gene`.`gene_biotype`',
		'b93574bf8a03f2d6f6486e920115e0d1' => '`Gene`.`annotation_version`',
		'1c4a3f5d90070e8ea1c62ca077df603e' => '`Gene`.`gene_description`',
		'8ca7a0c53312b8ae3cfa40a9d814adac' => '`Gene`'
	),
	'fields' => array(
		'47cba37bb7792f95f7499f6996d48351' => array(
			(int) 0 => '`Gene`.`id`',
			(int) 1 => '`Gene`.`gene_version`',
			(int) 2 => '`Gene`.`tax_id`',
			(int) 3 => '`Gene`.`assembly`',
			(int) 4 => '`Gene`.`chromosome`',
			(int) 5 => '`Gene`.`strand`',
			(int) 6 => '`Gene`.`start`',
			(int) 7 => '`Gene`.`end`',
			(int) 8 => '`Gene`.`gene_name`',
			(int) 9 => '`Gene`.`gene_source`',
			(int) 10 => '`Gene`.`gene_biotype`',
			(int) 11 => '`Gene`.`annotation_version`',
			(int) 12 => '`Gene`.`gene_description`'
		)
	)
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??