Warning (512): _cake_core_ cache was unable to write 'cake_dev_eng' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'cake_dev_eng'
$value = array(
	'LC_MESSAGES' => array()
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_list'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_list'
$value = array(
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	(int) 1 => 'experiment',
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	(int) 3 => 'genes',
	(int) 4 => 'go_annotations',
	(int) 5 => 'homologues',
	(int) 6 => 'repeats',
	(int) 7 => 'study',
	(int) 8 => 'synonyms',
	(int) 9 => 'transcripts'
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_transcripts' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_transcripts'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165

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                ),
                E_USER_WARNING
            );
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$value = array(
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		'collate' => 'latin1_swedish_ci',
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		'collate' => 'latin1_swedish_ci',
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		'length' => (int) 64,
		'key' => 'index',
		'collate' => 'latin1_swedish_ci',
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		'collate' => 'latin1_swedish_ci',
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		'charset' => 'latin1'
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	'transcript_biotype' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 128,
		'collate' => 'latin1_swedish_ci',
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		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
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)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 372
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

• HOME
• GENES
• TRANSCRIPTS
• HELP
• CONTACT

Transcript Info
Description:
Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
ENSMUST00000190337	Eya1-004	ENSMUSG00000025932	10090	-	1:14170643-14304570	protein_coding

Expression Patterns Split around values. Cell Line Name Tissue Condition Heat Map Numeric Values Transcript ID C166 Tie2+ EC ENSMUST00000190337 0.064±0.03 0.023±0.01

Conserved Regions
Not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000132	IGI	establishment of mitotic spindle orientation
GO:0001656	IMP	metanephros development
GO:0001657	IGI	ureteric bud development
GO:0001658	IGI	branching involved in ureteric bud morphogenesis
GO:0003151	IMP	outflow tract morphogenesis
GO:0003723	IDA	RNA binding
GO:0004725	IDA	protein tyrosine phosphatase activity
GO:0005515	IPI	protein binding
GO:0005634	ISS	nucleus
GO:0005737	IDA	cytoplasm
GO:0006302	ISS	double-strand break repair
GO:0006351	IEA	transcription, DNA-templated
GO:0006470	IDA	protein dephosphorylation
GO:0007389	IGI	pattern specification process
GO:0007501	IDA	mesodermal cell fate specification
GO:0009887	IMP	organ morphogenesis
GO:0010212	ISS	response to ionizing radiation
GO:0014706	IGI	striated muscle tissue development
GO:0016576	ISS	histone dephosphorylation
GO:0016925	IDA	protein sumoylation
GO:0032993	IDA	protein-DNA complex
GO:0034613	IMP	cellular protein localization
GO:0035088	IMP	establishment or maintenance of apical/basal cell polarity
GO:0035335	IEA	peptidyl-tyrosine dephosphorylation
GO:0035909	IMP	aorta morphogenesis
GO:0042472	IMP	inner ear morphogenesis
GO:0042473	IMP	outer ear morphogenesis
GO:0042474	IMP	middle ear morphogenesis
GO:0043234	IDA	protein complex
GO:0045165	IMP	cell fate commitment
GO:0045664	IMP	regulation of neuron differentiation
GO:0045739	ISS	positive regulation of DNA repair
GO:0045747	IMP	positive regulation of Notch signaling pathway
GO:0045893	IDA	positive regulation of transcription, DNA-templated
GO:0045944	IGI	positive regulation of transcription from RNA polymerase II promoter
GO:0046872	IEA	metal ion binding
GO:0048665	IGI	neuron fate specification
GO:0048704	IMP	embryonic skeletal system morphogenesis
GO:0048752	IMP	semicircular canal morphogenesis
GO:0048856	IGI	anatomical structure development
GO:0050679	IMP	positive regulation of epithelial cell proliferation
GO:0060037	IMP	pharyngeal system development
GO:0060487	IGI	lung epithelial cell differentiation
GO:0071599	IGI	otic vesicle development
GO:0071600	IMP	otic vesicle morphogenesis
GO:0072513	IGI	positive regulation of secondary heart field cardioblast proliferation
GO:0090103	IMP	cochlea morphogenesis
GO:2001240	IMP	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSDART00000134221	eya1-002	protein_coding	Danio_rerio	0	1083
ENSDART00000012253	eya1-201	protein_coding	Danio_rerio	0	1003
ENSDART00000081595	eya1-202	protein_coding	Danio_rerio	0	915
ENSDART00000136443	eya1-001	protein_coding	Danio_rerio	0	915
ENSDART00000138119	eya1-003	processed_transcript	Danio_rerio	0	254
ENSDART00000142058	eya1-004	protein_coding	Danio_rerio	0	211
ENST00000303824	EYA1-010	protein_coding	Homo_sapiens	0	2477
ENST00000340726	EYA1-001	protein_coding	Homo_sapiens	0	2555
ENST00000355286	EYA4-008	protein_coding	Homo_sapiens	0	470
ENST00000367895	EYA4-001	protein_coding	Homo_sapiens	0	470
ENST00000388740	EYA1-201	protein_coding	Homo_sapiens	0	2296
ENST00000388741	EYA1-012	protein_coding	Homo_sapiens	0	2309
ENST00000388742	EYA1-002	protein_coding	Homo_sapiens	0	2654
ENST00000388743	EYA1-011	protein_coding	Homo_sapiens	0	2667
ENST00000419131	EYA1-005	protein_coding	Homo_sapiens	0	1343
ENST00000422295	EYA1-007	retained_intron	Homo_sapiens	0	324
ENST00000465115	EYA1-003	nonsense_mediated_decay	Homo_sapiens	0	1929
ENST00000493349	EYA1-008	nonsense_mediated_decay	Homo_sapiens	0	436
ENST00000496494	EYA1-004	retained_intron	Homo_sapiens	0	2015
ENST00000531901	EYA4-009	protein_coding	Homo_sapiens	0	470

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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

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                ),
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		'9b1c568cf65fba8e7e2de6dc1b67b3f9' => '`Transcript`.`chromosome`',
		'6e01bbef387a58c2ce7c4c3844dc88c0' => '`Transcript`.`strand`',
		'60b04f112f50bbdce828cbef65efa0b9' => '`Transcript`.`start`',
		'f1cac05c79ebe8dd755656a25ec597a7' => '`Transcript`.`end`',
		'cb77e27a33acde1f1d541f16aa9c2a8e' => '`Transcript`.`transcript_name`',
		'4c7958e621b5890aa3788835d12d3c8c' => '`Transcript`.`transcript_source`',
		'a99f810917ca747fa263ac35165d3bbd' => '`Transcript`.`transcript_biotype`',
		'85718a755d73a123c8cbafa875fd8c34' => '`Transcript`.`annotation_version`',
		'8c6497837140572ea11ac9f79b9f25eb' => '`Transcript`'
	),
	'fields' => array(
		'9a798879191c21ec35c3dee0b33210e1' => array(
			(int) 0 => '`Transcript`.`id`',
			(int) 1 => '`Transcript`.`fk_gene_id`',
			(int) 2 => '`Transcript`.`transcript_version`',
			(int) 3 => '`Transcript`.`tax_id`',
			(int) 4 => '`Transcript`.`assembly`',
			(int) 5 => '`Transcript`.`chromosome`',
			(int) 6 => '`Transcript`.`strand`',
			(int) 7 => '`Transcript`.`start`',
			(int) 8 => '`Transcript`.`end`',
			(int) 9 => '`Transcript`.`transcript_name`',
			(int) 10 => '`Transcript`.`transcript_source`',
			(int) 11 => '`Transcript`.`transcript_biotype`',
			(int) 12 => '`Transcript`.`annotation_version`'
		)
	)
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??