ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026193 Fn1 10090 - 1:71585520-71653200 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055226 Fn1-001 71585524-71653175 protein_coding
  ENSMUST00000185408 Fn1-012 71585526-71609567 retained_intron
  ENSMUST00000186129 Fn1-002 71585524-71653200 protein_coding
  ENSMUST00000186575 Fn1-018 71586861-71591071 retained_intron
  ENSMUST00000186613 Fn1-014 71629457-71641288 nonsense_mediated_decay
  ENSMUST00000186736 Fn1-013 71645643-71653172 protein_coding
  ENSMUST00000186879 Fn1-009 71644477-71653172 retained_intron
  ENSMUST00000186940 Fn1-010 71642825-71653161 protein_coding
  ENSMUST00000186985 Fn1-016 71598360-71602376 nonsense_mediated_decay
  ENSMUST00000187627 Fn1-017 71590097-71600368 nonsense_mediated_decay
  ENSMUST00000187938 Fn1-007 71585523-71653172 protein_coding
  ENSMUST00000188092 Fn1-015 71600387-71602844 retained_intron
  ENSMUST00000188674 Fn1-005 71585523-71653172 protein_coding
  ENSMUST00000188894 Fn1-003 71585520-71653172 protein_coding
  ENSMUST00000189160 Fn1-011 71604097-71624344 retained_intron
  ENSMUST00000189821 Fn1-006 71585523-71653172 protein_coding
  ENSMUST00000190780 Fn1-008 71585524-71653172 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000055226ENSMUST00000186129ENSMUST00000187938ENSMUST00000188674ENSMUST00000188894ENSMUST00000189160ENSMUST00000189821ENSMUST00000190780
Transcript ID C166 Tie2+ EC mES
ENSMUST00000055226 466.768±153.45 2.288±2.13 172.369±26.58
ENSMUST00000186129 N/A 133.937±12.94 N/A
ENSMUST00000187938 N/A N/A 55.423±0.00
ENSMUST00000188674 N/A 1.822±0.00 N/A
ENSMUST00000188894 N/A 152.005±10.78 61.247±2.22
ENSMUST00000189160 N/A 0.802±0.00 N/A
ENSMUST00000189821 N/A 0.146±0.00 N/A
ENSMUST00000190780 87.370±18.58 56.015±6.20 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005MI CIL_0005MI_0002 CGP
CIL_0005MJ CIL_0005MJ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0002020 IEA protease binding
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005577 IEA fibrinogen complex
GO:0005578 TAS proteinaceous extracellular matrix
GO:0005604 IDA basement membrane
GO:0005605 IDA basal lamina
GO:0005615 IEA extracellular space
GO:0005793 IEA endoplasmic reticulum-Golgi intermediate compartment
GO:0006953 IEA acute-phase response
GO:0007044 IDA cell-substrate junction assembly
GO:0007155 IDA cell adhesion
GO:0007160 IDA cell-matrix adhesion
GO:0007161 IDA calcium-independent cell-matrix adhesion
GO:0008201 IEA heparin binding
GO:0008360 IEA regulation of cell shape
GO:0010952 IDA positive regulation of peptidase activity
GO:0016324 IDA apical plasma membrane
GO:0016504 IDA peptidase activator activity
GO:0018149 IEA peptide cross-linking
GO:0031012 IDA extracellular matrix
GO:0033622 IEA integrin activation
GO:0034446 IEA substrate adhesion-dependent cell spreading
GO:0035987 IEA endodermal cell differentiation
GO:0042060 IMP wound healing
GO:0045773 IDA positive regulation of axon extension
GO:0070062 IEA extracellular vesicular exosome
GO:0072562 IEA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006526 fn1b protein_coding Danio_rerio
ENSDARG00000019815 fn1a protein_coding Danio_rerio
ENSG00000115414 FN1 fibronectin 1 protein_coding Homo_sapiens

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