ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026288 Inpp5d 10090 + 1:87620312-87720507 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042275 Inpp5d-002 87620362-87720503 protein_coding
  ENSMUST00000072999 Inpp5d-004 87620398-87720503 nonsense_mediated_decay
  ENSMUST00000163222 Inpp5d-008 87620356-87635379 retained_intron
  ENSMUST00000163548 Inpp5d-011 87709341-87712159 processed_transcript
  ENSMUST00000163576 Inpp5d-010 87621674-87667916 protein_coding
  ENSMUST00000164592 Inpp5d-007 87620389-87645154 processed_transcript
  ENSMUST00000165554 Inpp5d-009 87620627-87667992 protein_coding
  ENSMUST00000167032 Inpp5d-005 87676239-87720502 protein_coding
  ENSMUST00000168783 Inpp5d-003 87620399-87719694 protein_coding
  ENSMUST00000169754 Inpp5d-001 87620312-87720507 protein_coding
  ENSMUST00000170300 Inpp5d-006 87676239-87720502 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000042275ENSMUST00000072999ENSMUST00000167032ENSMUST00000168783ENSMUST00000169754ENSMUST00000170300
Transcript ID C166 Tie2+ EC mES
ENSMUST00000042275 N/A 2.728±1.40 0.345±0.00
ENSMUST00000072999 N/A 1.416±0.00 N/A
ENSMUST00000167032 0.038±0.00 N/A N/A
ENSMUST00000168783 0.014±0.00 2.900±1.72 N/A
ENSMUST00000169754 N/A 3.148±1.37 1.319±0.00
ENSMUST00000170300 0.024±0.01 N/A 1.339±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003HY CIL_0003HY_0002 CGP
CIL_0003HZ CIL_0003HZ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004445 IDA inositol-polyphosphate 5-phosphatase activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006915 IEA apoptotic process
GO:0008285 IDA negative regulation of cell proliferation
GO:0008340 IMP determination of adult lifespan
GO:0009968 IMP negative regulation of signal transduction
GO:0016064 IMP immunoglobulin mediated immune response
GO:0016311 IDA dephosphorylation
GO:0017124 IDA SH3 domain binding
GO:0030853 IMP negative regulation of granulocyte differentiation
GO:0030889 IMP negative regulation of B cell proliferation
GO:0034594 IDA phosphatidylinositol trisphosphate phosphatase activity
GO:0035556 IMP intracellular signal transduction
GO:0043065 IMP positive regulation of apoptotic process
GO:0045409 IMP negative regulation of interleukin-6 biosynthetic process
GO:0045579 IMP positive regulation of B cell differentiation
GO:0045621 IMP positive regulation of lymphocyte differentiation
GO:0045648 IMP positive regulation of erythrocyte differentiation
GO:0045656 IMP negative regulation of monocyte differentiation
GO:0045659 IMP negative regulation of neutrophil differentiation
GO:0045671 IMP negative regulation of osteoclast differentiation
GO:0045779 IMP negative regulation of bone resorption
GO:0046856 IEA phosphatidylinositol dephosphorylation
GO:0050777 IMP negative regulation of immune response
GO:0050869 IMP negative regulation of B cell activation
GO:0051425 IDA PTB domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074283 inpp5d protein_coding Danio_rerio
ENSG00000168918 INPP5D inositol polyphosphate-5-phosphatase, 145kDa protein_coding Homo_sapiens

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