ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026425 Srgap2 10090 - 1:131285251-131527352 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000097588 Srgap2-001 131285251-131527347 protein_coding
  ENSMUST00000185445 Srgap2-009 131411800-131514232 protein_coding
  ENSMUST00000185596 Srgap2-005 131296641-131364064 protein_coding
  ENSMUST00000186543 Srgap2-004 131295218-131527347 protein_coding
  ENSMUST00000187042 Srgap2-012 131289358-131300453 protein_coding
  ENSMUST00000187273 Srgap2-010 131436675-131504366 protein_coding
  ENSMUST00000188437 Srgap2-011 131319535-131332263 retained_intron
  ENSMUST00000188604 Srgap2-013 131295756-131296380 processed_transcript
  ENSMUST00000188770 Srgap2-006 131295221-131344547 protein_coding
  ENSMUST00000189892 Srgap2-008 131295219-131311065 processed_transcript
  ENSMUST00000189893 Srgap2-002 131362026-131527352 retained_intron
  ENSMUST00000190336 Srgap2-007 131294988-131333070 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000097588ENSMUST00000186543
Transcript ID C166 Tie2+ EC mES
ENSMUST00000097588 10.728±2.68 7.223±4.38 4.363±1.01
ENSMUST00000186543 11.592±0.37 9.952±0.00 11.043±1.83

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005VZ CIL_0005VZ_0002 CGP
CIL_00012Y CIL_00012Y_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0005743 IDA mitochondrial inner membrane
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0007165 IEA signal transduction
GO:0014069 IDA postsynaptic density
GO:0021816 IMP extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
GO:0030054 IEA cell junction
GO:0030675 IDA Rac GTPase activator activity
GO:0032855 IDA positive regulation of Rac GTPase activity
GO:0042803 IDA protein homodimerization activity
GO:0044327 ISS dendritic spine head
GO:0045211 IDA postsynaptic membrane
GO:0045335 IDA phagocytic vesicle
GO:0046847 IDA filopodium assembly
GO:0048365 IDA Rac GTPase binding
GO:0048812 IMP neuron projection morphogenesis
GO:0051014 ISS actin filament severing
GO:0060996 IMP dendritic spine development
GO:2001223 ISS negative regulation of neuron migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032161 srgap2a protein_coding Danio_rerio
ENSG00000171943 SRGAP2C SLIT-ROBO Rho GTPase activating protein 2C protein_coding Homo_sapiens
ENSG00000196369 SRGAP2B SLIT-ROBO Rho GTPase activating protein 2B protein_coding Homo_sapiens

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