ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026586 Prrx1 10090 - 1:163245119-163313710 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027878 Prrx1-001 163245119-163313710 protein_coding
  ENSMUST00000075805 Prrx1-002 163245119-163313672 protein_coding
  ENSMUST00000174098 Prrx1-003 163282819-163313671 retained_intron
  ENSMUST00000174397 Prrx1-004 163252866-163313668 protein_coding
  ENSMUST00000183691 Prrx1-005 163247577-163289224 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000027878ENSMUST00000075805ENSMUST00000174397ENSMUST00000183691
Transcript ID C166 Tie2+ EC mES
ENSMUST00000027878 1.986±1.29 0.017±0.01 0.105±0.08
ENSMUST00000075805 0.272±0.10 0.170±0.12 0.005±0.00
ENSMUST00000174397 0.947±0.00 0.006±0.00 0.012±0.00
ENSMUST00000183691 2.033±1.07 0.140±0.12 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0002053 IGI positive regulation of mesenchymal cell proliferation
GO:0003677 IDA DNA binding
GO:0005634 IDA nucleus
GO:0005730 IEA nucleolus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0030326 IGI embryonic limb morphogenesis
GO:0042472 IGI inner ear morphogenesis
GO:0042474 IMP middle ear morphogenesis
GO:0043565 IEA sequence-specific DNA binding
GO:0045880 IGI positive regulation of smoothened signaling pathway
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0048704 IGI embryonic skeletal system morphogenesis
GO:0048844 IGI artery morphogenesis
GO:0051216 IMP cartilage development
GO:0060021 IMP palate development
GO:0071837 IPI HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033971 prrx1a protein_coding Danio_rerio
ENSDARG00000042027 prrx1b protein_coding Danio_rerio
ENSG00000116132 PRRX1 paired related homeobox 1 protein_coding Homo_sapiens

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