ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: paired related homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116132 PRRX1 9606 + 1:170662728-170739419 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000239461 PRRX1-002 170663906-170739419 protein_coding
  ENST00000367760 PRRX1-001 170663134-170736508 protein_coding
  ENST00000476867 PRRX1-003 170722617-170736399 processed_transcript
  ENST00000485529 PRRX1-007 170730206-170736233 processed_transcript
  ENST00000495280 PRRX1-004 170722645-170736233 processed_transcript
  ENST00000496573 PRRX1-006 170730446-170736233 processed_transcript
  ENST00000497230 PRRX1-005 170663937-170729021 protein_coding
  ENST00000553786 PRRX1-008 170662728-170719903 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000239461ENST00000367760ENST00000476867ENST00000485529ENST00000495280ENST00000497230ENST00000553786
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000239461 0.108±0.24 0.036±0.00 0.041±0.06
ENST00000367760 0.033±0.01 N/A 0.026±0.01
ENST00000476867 0.146±0.06 N/A 0.164±0.05
ENST00000485529 0.280±0.05 1.026±0.00 0.250±0.09
ENST00000495280 0.345±0.01 N/A 0.133±0.00
ENST00000497230 0.066±0.09 0.084±0.00 0.031±0.05
ENST00000553786 N/A N/A 0.069±0.02

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000284 CIL_000284_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0002053 IEA positive regulation of mesenchymal cell proliferation
GO:0003677 IEA DNA binding
GO:0003713 TAS transcription coactivator activity
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0030326 IEA embryonic limb morphogenesis
GO:0042472 IEA inner ear morphogenesis
GO:0042474 IEA middle ear morphogenesis
GO:0043565 IEA sequence-specific DNA binding
GO:0045880 IEA positive regulation of smoothened signaling pathway
GO:0048701 IEA embryonic cranial skeleton morphogenesis
GO:0048704 IEA embryonic skeletal system morphogenesis
GO:0048844 IEA artery morphogenesis
GO:0051216 IEA cartilage development
GO:0060021 IEA palate development
GO:0071837 IEA HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033971 prrx1a protein_coding Danio_rerio
ENSDARG00000042027 prrx1b protein_coding Danio_rerio
ENSMUSG00000026586 Prrx1 protein_coding Mus_musculus

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