ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027168 Pax6 10090 + 2:105668900-105697364 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000090391 Pax6-013 105676128-105697071 protein_coding
  ENSMUST00000090397 Pax6-011 105675191-105697242 protein_coding
  ENSMUST00000111082 Pax6-012 105676129-105697361 protein_coding
  ENSMUST00000111083 Pax6-009 105675527-105697071 protein_coding
  ENSMUST00000111085 Pax6-008 105675433-105697344 protein_coding
  ENSMUST00000111086 Pax6-001 105668900-105697364 protein_coding
  ENSMUST00000111087 Pax6-002 105668900-105697364 protein_coding
  ENSMUST00000111088 Pax6-004 105671860-105697242 protein_coding
  ENSMUST00000123000 Pax6-025 105683754-105684943 retained_intron
  ENSMUST00000123063 Pax6-003 105668920-105696462 processed_transcript
  ENSMUST00000135412 Pax6-020 105682508-105692265 processed_transcript
  ENSMUST00000138365 Pax6-021 105682537-105691723 processed_transcript
  ENSMUST00000140173 Pax6-019 105682463-105692233 processed_transcript
  ENSMUST00000142772 Pax6-015 105668935-105683870 protein_coding
  ENSMUST00000145744 Pax6-022 105682547-105692243 processed_transcript
  ENSMUST00000146803 Pax6-026 105685322-105697364 processed_transcript
  ENSMUST00000147923 Pax6-005 105673963-105675876 processed_transcript
  ENSMUST00000147946 Pax6-027 105692483-105693125 retained_intron
  ENSMUST00000153011 Pax6-018 105679867-105692222 processed_transcript
  ENSMUST00000153639 Pax6-016 105675191-105675822 retained_intron
  ENSMUST00000154302 Pax6-024 105681712-105684982 retained_intron
  ENSMUST00000154643 Pax6-014 105682535-105696353 retained_intron
  ENSMUST00000155081 Pax6-023 105682637-105691694 processed_transcript
  ENSMUST00000156216 Pax6-017 105678391-105685795 protein_coding
  ENSMUST00000167211 Pax6-201 105675513-105697361 protein_coding
  ENSMUST00000172990 Pax6-010 105675109-105675972 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECENSMUST00000090397ENSMUST00000123063ENSMUST00000146803ENSMUST00000153011ENSMUST00000154302
Transcript ID C166 Tie2+ EC
ENSMUST00000090397 N/A 0.039±0.00
ENSMUST00000123063 N/A 0.126±0.00
ENSMUST00000146803 0.008±0.00 0.097±0.05
ENSMUST00000153011 N/A 0.092±0.00
ENSMUST00000154302 N/A 0.067±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00096J CIL_00096J_0002 VISTA
CIL_0007PY CIL_0007PY_0002 VISTA
CIL_0007JA CIL_0007JA_0005 UCNEbase
CIL_000914 CIL_000914_0002 VISTA
CIL_00017T CIL_00017T_0002 CGP
CIL_0007XG CIL_0007XG_0002 VISTA
CIL_0008UP CIL_0008UP_0002 VISTA
CIL_0007UQ CIL_0007UQ_0002 VISTA
CIL_0008KI CIL_0008KI_0002 VISTA
CIL_00096G CIL_00096G_0002 VISTA
CIL_0000ZD CIL_0000ZD_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000132 IMP establishment of mitotic spindle orientation
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001227 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001568 IEA blood vessel development
GO:0001709 IMP cell fate determination
GO:0001755 IEA neural crest cell migration
GO:0001764 IMP neuron migration
GO:0001933 IMP negative regulation of protein phosphorylation
GO:0002052 IMP positive regulation of neuroblast proliferation
GO:0002064 IEA epithelial cell development
GO:0002088 IMP lens development in camera-type eye
GO:0003309 IMP type B pancreatic cell differentiation
GO:0003310 IEA pancreatic A cell differentiation
GO:0003322 IMP pancreatic A cell development
GO:0003677 IDA DNA binding
GO:0003680 IEA AT DNA binding
GO:0003682 IDA chromatin binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 IDA nucleus
GO:0005667 TAS transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006357 IMP regulation of transcription from RNA polymerase II promoter
GO:0006366 IMP transcription from RNA polymerase II promoter
GO:0007224 IDA smoothened signaling pathway
GO:0007409 IMP axonogenesis
GO:0007411 IMP axon guidance
GO:0007417 IEA central nervous system development
GO:0007420 IMP brain development
GO:0007435 IMP salivary gland morphogenesis
GO:0008134 IPI transcription factor binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0009611 IEA response to wounding
GO:0009786 IMP regulation of asymmetric cell division
GO:0009950 IMP dorsal/ventral axis specification
GO:0009952 IMP anterior/posterior pattern specification
GO:0009953 IMP dorsal/ventral pattern formation
GO:0010468 IMP regulation of gene expression
GO:0010628 IMP positive regulation of gene expression
GO:0010975 IEA regulation of neuron projection development
GO:0019901 IPI protein kinase binding
GO:0021510 IEA spinal cord development
GO:0021543 IMP pallium development
GO:0021549 IEA cerebellum development
GO:0021593 IEA rhombomere morphogenesis
GO:0021772 IEA olfactory bulb development
GO:0021778 IMP oligodendrocyte cell fate specification
GO:0021796 IMP cerebral cortex regionalization
GO:0021797 IMP forebrain anterior/posterior pattern specification
GO:0021798 IMP forebrain dorsal/ventral pattern formation
GO:0021902 IMP commitment of neuronal cell to specific neuron type in forebrain
GO:0021905 IMP forebrain-midbrain boundary formation
GO:0021912 IMP regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
GO:0021913 IMP regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
GO:0021918 IMP regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment
GO:0021978 IMP telencephalon regionalization
GO:0021983 IMP pituitary gland development
GO:0022027 IEA interkinetic nuclear migration
GO:0023019 IDA signal transduction involved in regulation of gene expression
GO:0030154 IMP cell differentiation
GO:0030216 IMP keratinocyte differentiation
GO:0030334 IMP regulation of cell migration
GO:0030858 IMP positive regulation of epithelial cell differentiation
GO:0030900 IMP forebrain development
GO:0030902 IEA hindbrain development
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032808 IMP lacrimal gland development
GO:0032869 IEA cellular response to insulin stimulus
GO:0033365 IMP protein localization to organelle
GO:0035035 IDA histone acetyltransferase binding
GO:0035690 IEA cellular response to drug
GO:0042462 IMP eye photoreceptor cell development
GO:0042593 IEA glucose homeostasis
GO:0042660 IEA positive regulation of cell fate specification
GO:0043010 IMP camera-type eye development
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044344 IEA cellular response to fibroblast growth factor stimulus
GO:0045165 IGI cell fate commitment
GO:0045471 IEA response to ethanol
GO:0045664 IEA regulation of neuron differentiation
GO:0045665 IGI negative regulation of neuron differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048505 IMP regulation of timing of cell differentiation
GO:0048596 IGI embryonic camera-type eye morphogenesis
GO:0048708 IMP astrocyte differentiation
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0050767 IMP regulation of neurogenesis
GO:0060041 IGI retina development in camera-type eye
GO:0061072 IEA iris morphogenesis
GO:0061303 IEA cornea development in camera-type eye
GO:0061351 IEA neural precursor cell proliferation
GO:0070094 IEA positive regulation of glucagon secretion
GO:0070410 IDA co-SMAD binding
GO:0070412 IDA R-SMAD binding
GO:0071333 IEA cellular response to glucose stimulus
GO:0071380 IEA cellular response to prostaglandin E stimulus
GO:0071837 IPI HMG box domain binding
GO:1901142 IEA insulin metabolic process
GO:2000178 IMP negative regulation of neural precursor cell proliferation
GO:2001224 IEA positive regulation of neuron migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045936 pax6b protein_coding Danio_rerio
ENSG00000007372 PAX6 paired box 6 protein_coding Homo_sapiens

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